[Mechanism of autophagy inhibition for sensitizing HeLa cell apoptosis induced by trichosanthin].

This research investigated the effect and mechanism of trichosanthin(TCS) in inducing autophagy and apoptosis of HeLa cells in cervical cancer. Two-step chromatography was used to prepare TCS. MTT assay was used to detect the inhibition effect of TCS on the proliferation of HeLa cells.

promotes the progression of colorectal cancer by interacting with E-cadherin.

Increasing evidence suggests that is involved in colorectal carcinogenesis. Previous studies have explored whether may trigger colonic epithelial-mesenchymal transition. The results of the present study demonstrated that enhances the proliferation and invasion of NCM460 cells compared with that of normal control and DH5α cells.