Experimental Investigation of a Novel Nanocomposite Particle Gel for Water Shutoff Treatment in Mature Oilfields.

Conventional preformed particle gels suffer from insufficient salt tolerance and weak mechanical properties after water absorption, which reduce the water shutoff effect in mature oilfields. In this paper, a nanocomposite particle gel (NCPG) is synthesized by copolymerization of acrylamide (AM) and 2-acrylamido-2-methylpropane sulfonic acid (AMPS) using laponite RD (LPT) as a physical cross-linker and ,-methylene-bisacrylamide (MBA) as a chemical cross-linker via in situ free radical polymerization. Compared with the NCPG without LPT, both the swelling rate and mechanical properties of NCPG added with LPT are found to be improved.

Phase Behavior of Internal Mixtures of Hydrocarbon-like Primary Organic Aerosol and Secondary Aerosol Based on Their Differences in Oxygen-to-Carbon Ratios.

The phase behavior, the number and type of phases, in atmospheric particles containing mixtures of hydrocarbon-like organic aerosol (HOA) and secondary organic aerosol (SOA) is important for predicting their impacts on air pollution, human health, and climate. Using a solvatochromic dye and fluorescence microscopy, we determined the phase behavior of 11 HOA proxies (O/C = 0-0.29) each mixed with 7 different SOA materials generated in environmental chambers (O/C 0.

Icariin regulates stem cell migration for endogenous repair of intervertebral disc degeneration by increasing the expression of chemotactic cytokines.

Background: Icariin (ICA) can promote the migration and bone formation of bone marrow mesenchymal stem cells. This study explored a potential role of ICA in recruiting stem cell niches (SCNs) within the intervertebral disc region (ISN)-derived stem cells (ISN-SCs) to treat intervertebral disc degeneration (IVDD).

Materials And Methods: EdU staining, transwell, and wound healing tests were used to analyze the function of ICA on ISN-SCs proliferation and migration ability.

Response of Properties and Chemicals to Preparation Parameters in the Oxidation Processing of Refined Montan Wax.

Refined montan wax (RMW) is a lignite-based chemical product with wide application and high added value. However, research on its processing and performance is very limited. Currently, four parameters in the key preparation procedure for the oxidation bleaching of RMW, including the concentration of two oxidants (HSO (P1) and CrO (P2)), oxidation time (P3), and the mass ratio of CrO used in two oxidation steps (P4), were systematically evaluated in regard to their impact on the properties and chemistry of RMW.

Development of a High-Strength and Adhesive Polyacrylamide Gel for Well Plugging.

Addition of melamine formaldehyde (MF) as a crosslinker containing hydroxymethyl to partially hydrolyzed poly(acrylamide) (HPAM) generated covalently crosslinked gels through chemically nucleophilic attack by hydroxymethyl groups to amide in an HPAM backbone, which was demonstrated by FTIR spectrum analysis and rheological studies. NHCl could act as a catalyst to reduce the gelation time from 7 days in dilute water to 8 h in the presence of 0.8 wt % NHCl.

Electroacupuncture relieves neuropathic pain by inhibiting degradation of the ecto-nucleotidase PAP in the dorsal root ganglions of CCI mice.

Background: Although electroacupuncture is widely used in chronic pain management, it is quite controversial due to its unclear mechanism. We hypothesised that EA alleviates pain by inhibiting degradation of the ecto-nucleotidase prostatic acid phosphatase (PAP) and facilitating ATP dephosphorylation in dorsal root ganglions (DRGs).

Methods: We applied EA in male C57 mice subjected to chronic constriction injury (CCI) and assessed extracellular ATP and 5'-nucleotidease expression in DRGs.

Cost-effectiveness of enfortumab vedotin in previously treated advanced urothelial carcinoma.

Background: Antibody-drug conjugates have recently been introduced as a treatment for advanced urothelial carcinoma. The EV-301 study demonstrated that enfortumab vedotin (EV) improved overall survival compared with conventional chemotherapy. To assess the cost-effectiveness of EV for the treatment of advanced urothelial carcinoma (UC) from a payer perspective in middle- and high-income countries.

An Ultralight Self-Powered Fire Alarm e-Textile Based on Conductive Aerogel Fiber with Repeatable Temperature Monitoring Performance Used in Firefighting Clothing.

Firefighting protective clothing is an essential equipment that can protect firefighters from burn injuries during the firefighting process. However, it is still a challenge to detect the damage of firefighting protective clothing at an early stage when firefighters are exposed to excessively high temperature in fire cases. Herein, an ultralight self-powered fire alarm electronic textile (SFA e-textile) based on conductive aerogel fiber that comprises calcium alginate (CA), FeO nanoparticles (FeO NPs), and silver nanowires (Ag NWs) was developed, which achieved ultrasensitive temperature monitoring and energy harvesting in firefighting clothing.

Impact of serine and serine synthesis genes on HS release in Saccharomyces cerevisiae during wine fermentation.

Excessive hydrogen sulfide (HS) during fermentation causes undesirable sensory properties in wine. In yeast, serine functions as a precursor in the biosynthesis of S-containing compounds, which facilitates HS consumption. To investigate the effect of serine on HS release and the underlying mechanism, extracellular and intracellular serine levels were separately increased under fermentation conditions.

Mixed neuroendocrine nonneuroendocrine neoplasms of the pancreas: a case report and literature review of pancreatic mixed neuroendocrine nonneuroendocrine neoplasm.

A 36-year-old woman underwent left lateral hepatic lobectomy and tumor enucleation of the pancreatic head due to the diagnosis of mixed neuroendocrine nonneuroendocrine neoplasms (MiNENs). Her past medical history revealed an ill-defined mass in the pancreatic uncinate (approximately 1 cm in size) and liver nodules in segment II, suggesting a pancreatic neuroendocrine tumor (pNET) and liver metastases. After the operation, pathological examination showed that the lesion in the pancreas was MiNEN.

A Bibliometric Analysis of Endoscopic Sedation Research: 2001-2020.

To evaluate endoscopic sedation research and predict research hot spots both quantitatively and qualitatively using bibliometric analysis. We extracted relevant publications from the Web of Science Core Collection (WoSCC) on 13 December 2020. We examined the retrieved data by bibliometric analysis (e.

Short-term efficacy and safety of TurboHawk atherectomy for in-stent restenosis in peripheral artery disease: a single-centre experience.

Background: Information regarding the efficacy of the TurboHawk atherectomy for the treatment of in-stent restenosis (ISR) in patients with peripheral artery disease (PAD) of the lower extremity is scarce. This study was performed to investigate the curative efficacy and safety of the TurboHawk system for ISR in PAD patients over 60 years old.

Methods: The TurboHawk atherectomy device was used to treat ISR in 28 patients with PAD.

Low-intensity ultrasound promotes uterine involution after cesarean section: the first multicenter, randomized, controlled clinical trial.

Objective: To evaluate the clinical efficacy and safety of low-intensity ultrasound (LIUS) in promoting uterine involution and relieving postpartum pain.

Methods: The randomized controlled clinical trial in this study was conducted at five centers in three regions across China from June 2014 to December 2014. A total of 498 subjects were randomly divided into two groups.

Model-based clinical note entity recognition for rheumatoid arthritis using bidirectional encoder representation from transformers.

Background: Rheumatoid arthritis (RA) is a disease of the immune system with a high rate of disability and there are a large amount of valuable disease diagnosis and treatment information in the clinical note of the electronic medical record. Artificial intelligence methods can be used to mine useful information in clinical notes effectively. This study aimed to develop an effective method to identify and classify medical entities in the clinical notes relating to RA and use the entity identification results in subsequent studies.

Perfluorooctane sulfonate aggravates CCl4-induced hepatic fibrosis via HMGB1/TLR4/Smad signaling.

Perfluorooctane sulfonate (PFOS) is a widespread environmental pollutant and may cause a variety of adverse health effects. The hepatotoxicity of PFOS has attracted particular attention, given the fact that the liver has one of the highest PFOS accumulations among human tissues. In this study, we revealed that subchronic PFOS exposure may exacerbate carbon tetrachloride (CCl )-induced liver fibrosis in animal models.

Resection of a giant sternal chondrosarcoma and chest wall reconstruction: a case report.

Chondrosarcomas are common bone carcinomas; however, they are uncommon in the sternum, and giant sternal tumors have rarely been reported in advanced-age patients. This study aimed to describe the clinical presentation, method of preoperative planning and surgery, and perioperative management of a giant sternal chondrosarcoma in an advanced-age patient. We describe the case of an 80-year-old woman who presented with a rare giant sternal chondrosarcoma.

powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexin 43Cx43/glucocorticoid receptor/brain-derived neurotrophic factor signaling pathway.

Powder (XYP) has been widely applied in China to treat stress-related illnesses, such as migraine, depression, Parkinson's disease, insomnia, and hypertension. Herein, this study aims to explore the effect of XYP on chronic unpredictable mild stress (CUMS)-induced depression and its underlying mechanisms. CUMS-induced depression rat models were established, they were subsequently randomly divided and treated with various conditions.

VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction.

Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this process remains unclear. VX765, a specific caspase-1 inhibitor, has been shown to have a protective effect against several diseases including sepsis, atherosclerosis, and glial inflammatory disease.

Lipid raft involvement in signal transduction in cancer cell survival, cell death and metastasis.

Lipid rafts are cholesterol- and sphingolipid-enriched specialized membrane domains within the plasma membrane. Lipid rafts regulate the density and activity of signal receptors by compartmentalizing them, promoting signalling cascades that play important roles in the survival, death and metastasis of cancer cells. In this review, we emphasize the current concept initially postulated by F.

Improvement of Basal Cell Carcinomas in Patients with Nevoid Basal Cell Carcinoma Syndrome Following by 5-Aminolevulinic Acid Photodynamic Therapy: A Case Report.

Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominant-inherited disease characterized by multiple basal cell carcinomas, multiple keratocystic odontogenic tumors, palmar and/or plantar pits. A 50-year-old male patient presented to our hospital with multiple plaques and maculopapular lesions on his face and trunk for more than 20 years. A skin biopsy revealed a number of discrete nests of basaloid cells in the dermis where the peripheral cells are arrayed like a palisade.

Clearance of HR-HPV within one year after focused ultrasound or loop electrosurgical excision procedure in patients with HSIL under 30.

Objective: To compare the clearance rate of high-risk human papillomavirus (HR-HPV) in patients with a high-grade squamous intraepithelial lesion (HSIL) 12 months after focused ultrasound (FUS) or loop electrosurgical excision procedure (LEEP), and analyze the influencing factors.

Methods: A retrospective cohort was established in HSIL patients with HR-HPV infection treated with FUS or LEEP from 2015 to 2019. The cohort consisted of 321 patients under 30 years of age, of which 119 patients received FUS and 202 patients received LEEP.

Identification and verification of key cancer genes associated with prognosis of colorectal cancer based on bioinformatics analysis.

Objectives: The biomarkers targeting colorectal cancer (CRC) prognosis are short of high accuracy and sensitivity in clinic. Through bioinformatics analysis, we aim to identify and confirm a series of key genes referred to the diagnosis and prognosis of CRC.

Methods: GSE31905, GSE35279, and GSE41657 were selected as complete RNA sequencing data sets of CRC and colorectal mucosa (CRM) tissues from the NCBI-GEO database, and the differentially expressed genes (DEGs) were analyzed.

Holographic pancake optics for thin and lightweight optical see-through augmented reality.

Holographic pancake optics have been designed and fabricated in eyewear display optics literature dating back to 1985, however, a see-through pancake optic solution has not been demonstrated to date. The key contribution here is the first full-color volume holographic pancake optic in an optical see-through configuration for applications in mobile augmented reality. Specifically, the full-color volume holographic pancake is combined with a flat lightguide in order to achieve the optical see-through property.