Higher Steroid Production in the Right Adrenal Gland Compared to the Left One in db/db Mice, a Model of Type 2 Diabetic Obesity.

Vertebrates exhibit a left-right asymmetry from the central structures to the peripheral paired endocrine organs. However, the asymmetries in paired endocrine glands and the pathological consequences of such asymmetries remain largely unknown. The adrenal gland constitutes a pair of peripheral end organs in the neuroendocrine system, responsible for producing steroid hormones under stimuli.

Thermostability-assisted limited proteolysis-coupled mass spectrometry for capturing drug target proteins and sites.

Background: Identifying drug-binding targets and their corresponding sites is crucial for drug discovery and mechanism studies. Limited proteolysis-coupled mass spectrometry (LiP-MS) is a sophisticated method used for the detection of compound and protein interactions. However, in some cases, LiP-MS cannot identify the target proteins due to the small structure changes or the lack of enrichment of low-abundant protein.

[Prescription and medication rules of traditional Chinese medicine for prevention and treatment of diabetic microangiopathy based on literature mining].

This study explored the prescription and medication rules of traditional Chinese medicine(TCM) in the prevention and treatment of diabetic microangiopathy based on literature mining. Relevant literature on TCM against diabetic microangiopathy was searched and prescriptions were collected. Microsoft Excel 2021 software was used to establish a prescription database, and an analysis was conducted on the frequency, properties, flavors, meridian tropism, and efficacy classifications of drugs.

Theoretical study on the interaction between acetone and BN monolayer doped with Ni for the clinical diagnosis of diabetes mellitus.

Endogenous volatile organic compounds (VOCs) in human exhaled gases can reflect human health status and be used for clinical diagnosis and health monitoring. Acetone is the sign VOC gases of diabetes mellitus. In order to find a potential material for the detection of acetone in the application of the clinical diagnosis of diabetes mellitus.

Two Quantum Proxy Blind Signature Schemes Based on Controlled Quantum Teleportation.

We present a scheme for teleporting an unknown, two-particle entangled state with a message from a sender (Alice) to a receiver (Bob) via a six-particle entangled channel. We also present another scheme for teleporting an unknown one-particle entangled state with a message transmitted in a two-way form between the same sender and receiver via a five-qubit cluster state. One-way hash functions, Bell-state measurements, and unitary operations are adopted in these two schemes.

Concrete Elastic Modulus Experimental Research Based on Theory of Capillary Tension.

The risk of cracking in the early stage is a critical indicator of the performance of concrete structures. Concrete cracked when the tensile stresses caused by deformation under restraint conditions exceeded its tensile strength. This research aims at an accurate prediction of shrinkage cracking of concrete under constraints.

UHPLC-qMS spectrum-effect relationships for Rhizoma Paridis extracts.

Rhizoma Paridis (RP) with significant anti-tumor and haemostatic effects, has been used as the raw material of many Traditional Chinese preparations. However, its active ingredients are still unclear. The present study aimed to discover bioactive ingredients from RP based on spectrum-relationship and chemometric methods.

Co-implantation of magnesium and zinc ions into titanium regulates the behaviors of human gingival fibroblasts.

Soft tissue sealing around implants acts as a barrier between the alveolar bone and oral environment, protecting implants from the invasion of bacteria or external stimuli. In this work, magnesium (Mg) and zinc (Zn) are introduced into titanium by plasma immersed ion implantation technology, and their effects on the behaviors of human gingival fibroblasts (HGFs) as well as the underlying mechanisms are investigated. Surface characterization confirms Mg and Zn exist on the surface in metallic and oxidized states.

ZnO@ZnS nanorod-array coated titanium: Good to fibroblasts but bad to bacteria.

Cell-selective toxic titanium is highly desired in clinical dental practice. Herein, based on the in situ conversion of ZnO to ZnO@ZnS, nanorod-array structured coatings with a controllable release features of zinc (Zn), has been successfully fabricated by a two-step hydrothermal method to endow titanium surface with cell-selectivity, i.e.

Influence of Steel Plates and Studs on Shrinkage Behavior and Cracking Potential of High-Performance Concrete.

To help designers develop solutions to overcome the cracking problem in steel-plate-reinforced concrete composite shear walls due to the concrete shrinkage, the influence of steel plates and studs on the shrinkage behavior of high-performance concrete (HPC), including restrained shrinkage strain, shrinkage strain gradient, and cracking potential, were theoretically and experimentally investigated in this study. A model for theoretical analysis was used to research the shrinkage performance of concrete that was restrained by steel plates and studs. The major parameters involved in the experiments include the thickness and material elastic modulus of the steel plate, in addition to the diameter, height, and number of studs.

Unsupervised multiscale color image segmentation based on MDL principle.

We present an unsupervised multiscale color image segmentation algorithm. The basic idea is to apply mean shift clustering to obtain an over-segmentation and then merge regions at multiple scales to minimize the minimum description length criterion. The performance on the Berkeley segmentation benchmark campares favorably with some existing approaches.