Publications by authors named "Qimin Sun"
Article Synopsis
- - The study investigates the slow progression and rapid recurrence of esophageal squamous dysplasia (ESD) in some patients, aiming to understand the underlying molecular mechanisms.
- - Researchers sequenced genomic data from 160 clinical samples and found that ESD has lower mutation and copy number alteration levels compared to esophageal squamous cell carcinoma (ESCC).
- - They identified a new driver gene related to ESD progression and found that miR-4292 could act as a non-invasive diagnostic marker, offering insights for early diagnosis and better identification of high-risk patients.
Introduction: Blood phosphorylated tau at threonine 217 (tau-PT217) is a newly established biomarker for Alzheimer's disease and postoperative delirium in patients. However, the mechanisms and consequences of acute changes in blood tau-PT217 remain largely unknown.
Methods: We investigated the effects of anesthesia/surgery on blood tau-PT217 in aged mice, and evaluated the associated changes in B cell populations, neuronal excitability in anterior cingulate cortex, and delirium-like behavior using positron emission tomography imaging, nanoneedle technology, flow cytometry, electrophysiology, and behavioral tests.