Bolus delivery of palonosetron through skin by tip-loaded dissolving microneedles with short-duration iontophoresis: A potential strategy to rapidly relieve emesis associated with chemotherapy.

The objective of this study was to investigate the feasibility of the bolus administration of PLS via skin by using dissolving microneedles of palonosetron hydrochloride (PLS-DMNs). Tip-loaded PLS-DMNs were fabricated by a casting method using sodium hyaluronate (HA) as DMNs-forming polymer. PLS-DMNs were shown to have a content of 118.

[Preliminary development of photoelastic resin occlusal film].

Purpose: To develop an occlusal film that can be intuitively and easily used clinically to observe the stress distribution of occlusion, based on the photoelastic resin material properties.

Methods: Using self-made silicone rubber vaginal mold, the epoxy resin occlusal films were poured into 2 different thickness and 4 different plasticizer ratio. The hardness and bitability were evaluated in 10 cases of natural dentition and 5 cases of complete denture dentition, while the bite blot was recorded using light bomb instrument at the same time.

[A primary study of color tolerance of anterior tooth crown prosthesis].

Objective: To study the color tolerance of anterior ceramic crown and seek an effective approach for color-matching of oral prostheses.

Methods: 30 single maxillary incisor ceramic prostheses and the corresponding nature teeth were measured by a digital camera in a steady environment for image taking and color measurement, which based on the standard recommended by CIE. The color tolerance was analyzed in two groups based on satisfaction and dissatisfaction of prostheses color-matching.

[Comparison of clinically used shade guide systems with color range of natural teeth].

Objective: To analyze the limitation of currently used shade guide systems comparing with color range of nature teeth.

Methods: Digital pictures of shade guide systems A (VITAPAN Classic), B (VINTAGE Halo), C (3D-MASTER), and 322 central incisors were taken under the same condition as light source of D65 with the observation method of d/0 degrees. The data obtained from nature tooth color were compared with the color range of three shade guide systems mentioned above in items of L * a * b */C * H degrees.

[A study of color measurement for vital teeth using digital camera].

Purpose: To evaluate the reliability and reasonability of tooth color matching by using the digital camera.

Methods: 322 maxillary incisors from 161 Asia volunteers aged between 20 to 40 years were recorded by a Canon EOS D60 digital camera in studio environment (D65 standard illuminant). Photographs were taken under a set exposure parameters( AE f/2.

[Circulating test and analysis of clasp retention].

Objective: To show the trend of the retention change during the circulation of the clasp dislodging and inserting, and to discuss the proper depth of the undercut for a specific clasp. It is also a basic study for the best designing of RPD.

Methods: The Chatillon force measuring instrument was used to record the variation of the retention of Co-Cr alloy casting Akers clasp when they were dislodging from undercuts of different depths (0.

[The relationship between clasp retention and the depth of undercut].

Objective: To study the relationship between the depth of undercut and the retention of clasp, as a basic information in clinic designing of clasp.

Methods: The Chatillon force measuring instrument was used to record the retention of 18 Co-Cr alloy casting Akers clasps when they were dislodging from undercuts of different depths (0.25 mm, 0.