Publications by authors named "Qiman Han"

Article Synopsis
  • The study investigates setup errors in pelvic Volumetric Modulated Arc Therapy (VMAT) for non-surgical primary cervical cancer patients using an onboard imaging system to improve radiotherapy accuracy.
  • A total of 132 patients were analyzed, revealing mean setup errors for the lateral, longitudinal, and vertical directions, with notable discrepancies in older patients.
  • The findings highlight the critical need for precise setup, especially along the Y-axis, and recommend iCBCT-guided radiotherapy to enhance treatment accuracy for cervical cancer patients, particularly the elderly.
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Thyroid-associated ophthalmopathy (TAO) is a hallmark autoimmune condition, and the treatment of TAO requires a multidisciplinary approach. Radiation therapy (RT) is a viable treatment option for active TAO, IMRT is a more precise technology in radiation oncology. This study aims to evaluate the efficacy, feasibility, and safety of orbital intensity-modulated radiation therapy (IMRT) in the treatment of TAO.

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Introduction: Alterations in the MET gene, including amplifications and exon 14 skipping mutations, have been identified as actionable oncogenic alterations. However, MET fusions are rarely detected in lung cancer, and their sensitivity to therapeutics has not been systematically analyzed.

Methods: The data from 30876 lung cancer patients from the LAVA database and 7966 patients from cBioPortal database were screened.

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Synopsis of recent research by authors named "Qiman Han"

  • - Qiman Han's recent research focuses on the precision and efficacy of radiation therapy techniques for various cancer treatments, including cervical cancer and thyroid-associated ophthalmopathy, highlighting the importance of advanced imaging systems and targeted approaches in oncology.
  • - In a clinical study, Han analyzed setup errors in Volumetric Modulated Arc Therapy (VMAT) for cervical cancer using iterative kV cone beam CT (iCBCT), emphasizing improvements in radiotherapy precision and patient outcomes.
  • - Another significant study by Han identified MET gene fusions in lung cancer as novel therapeutic targets, demonstrating their sensitivity to MET inhibitors, thereby contributing to the understanding of actionable alterations in cancer treatment paradigms.*