Glutamate Chemical Exchange Saturation Transfer (GluCEST) Magnetic Resonance Imaging of Rat Brain With Acute Carbon Monoxide Poisoning.

Objectives: To evaluate the diagnostic and prognostic values of glutamate chemical exchange saturation transfer (GluCEST) magnetic resonance imaging as a quantitative method for pathogenetic research and clinical application of carbon monoxide (CO) poisoning-induced encephalopathy combined with the proton magnetic resonance spectroscopy (H-MRS) and the related histopathological and behavioral changes.

Methods: A total of 63 Sprague-Dawley rats were randomly divided into four groups. Group A ( = 12) was used for animal modeling verification; Group B ( = 15) was used for magnetic resonance molecular imaging, Group C ( = 15) was used for animal behavior experiments, and Group D ( = 21) was used for histopathological examination.

Ectopic thyroid gland located on the L4 vertebral body: A case report.

Rationale: The prevalence of ectopic thyroid is extremely low, with the condition observed in approximately 1 in 100,000 to 300,000 people. Thyroid gland ectopia develops as a result of the presence of developmental abnormalities during the migration of the thyroid anlage from the floor of the primitive foregut to its final position in the neck. Ectopic thyroid tissue is commonly observed in the lingual region, but can also present in other head and neck regions, as well as regions located at a large distance from the neck.

Microstructural and Neurochemical Changes in the Rat Brain After Diffuse Axonal Injury.

Background: Diffuse axonal injury (DAI) is one of the devastating types of traumatic brain injury, but is difficult to detect on conventional imaging in its early stages.

Purpose: To test the technical feasibility and diagnostic value of diffusion kurtosis imaging (DKI) and glutamate chemical exchange saturation transfer (GluCEST) imaging in the brain after DAI.

Study Type: Prospective.