Publications by authors named "Qilin Zeng"

Atomic force microscope (AFM) is an important nano-scale surface characterization and measurement method. Raster scanning method (RSM), widely used in AFMs, faces limitations on scanning speed and imaging accuracy. In this paper, an isotropic linear scanning method (ILSM) is proposed to improve the AFM imaging performance.

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  • This text discusses a new diagnostic system called Cpn-ERA-CRISPR/Cas12a designed to detect a specific intracellular pathogen responsible for respiratory diseases, which is a major public health issue.
  • The system combines enzymatic recombination amplification (ERA) with the CRISPR/Cas12a technology, enabling detection via fluorescence and lateral flow methods in as little as 15 to 30 minutes.
  • The system demonstrated high specificity by not reacting with other pathogens, achieved 100% detection accuracy in clinical samples, and shows promise for use in community hospitals.
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  • * By using subtractive genomics and metabolic pathway analysis, researchers identified two proteins, B5ZC96 and B5ZAH8, as potential therapeutic targets for Ureaplasma infections.
  • * The discovery of these protein targets is a key step toward developing new treatment strategies that could effectively combat drug-resistant infections, potentially reducing side effects due to their specificity.
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Current real-time direction judgment systems are inaccurate and insensitive, as well as limited by the sampling rate of analog-to-digital converters. To address this problem, we propose a dynamic real-time direction judgment system based on an integral dual-frequency laser interferometer and field-programmable gate array technology. The optoelectronic signals resulting from the introduction of a phase subdivision method based on the amplitude resolution of the laser interferometer when measuring displacement are analyzed.

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Background: Atherosclerosis (AS), a chronic inflammatory vascular disease, is a cause of heart attack and ischemic stroke. Tripartite motif-containing protein 59 (TRIM59), a member of the tripartite motif family, has been reported to be involved in inflammatory diseases. This study was to investigate the role of TRIM59 in oxidized low-density lipoprotein (ox-LDL)-induced endothelial cells and examine the mechanism of TRIM59.

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In this paper, to separate and compensate the nonlinear error in the grating interferometer, we analyze the source and generation mechanism of this error, deduce the nonlinear error model of the measured signal and the calculated phase signal, and study the characteristics of the established nonlinear error model. The reason why the frequency multiples of ideal phase signals and higher-order nonlinear errors caused by ghost reflections and angular errors of the laser's z-axis are not integers is explained. Then, a nonlinear error separation and compensation method based on cross-correlation coefficient is proposed.

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In this study, a subnanometer heterodyne interference signal processing algorithm with a dynamic filter is proposed. The algorithm can effectively reduce the measurement error caused by the noise introduced in the optical path and circuit. Because of the low signal-to-noise ratio of the measurement signal, a dynamic filter with variable coefficients is designed.

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In order to avoid the detrimental effects of excessive noise in the phase fringe patterns of a laser digital interferometer over the accuracy of phase unwrapping and the successful detection of mechanical fatigue defects, an effective method of adaptive multidirectional frequency domain filtering is introduced based on the characteristics of the energy spectrum of localized wrapped phase patterns. Not only can this method automatically set the cutoff frequency, but it can also effectively filter out noise while preserving the image edge information. Compared with the sine and cosine transform filtering and the multidirectional frequency domain filtering, the experimental results demonstrate that the image filtered by our method has the fewest number of residues and is the closest to the noise-free image, compared to the two aforementioned methods, demonstrating the effectiveness of this adaptive multidirectional frequency domain filter.

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