Comparison of two conchal formers for nonsurgical correction on Conchal Crus.

Objectives: Conchal Crus is a kind of congenital auricular deformation which is often overlooked. Few studies reported a large number of cases. We compared the efficacy of EarWell and self-made conchal formers on Conchal Crus to summarize our experience of correction and to find out the influencing factors.

[An observation of long term effect of one-stage hearing reconstruction on tympanosclerosis].

To observe the long-term hearing stability of patients with tympanosclerosis after one-stage hearing reconstruction. Forty-one patients with tympanosclerosis were included in the study. Their puretone thresholds before operation and those at 3 months, 6 months, 1 year, 2 to 5 years after operation were retrospectively analyzed.

Vincamine exerts protective effect on spiral ganglion neurons in endolymphatic hydrops guinea pig models.

The aim of this study was to investigate the protective effects of vincamine in endolymphatic hydrops (ELH). After ELH guinea pigs treated by vincamine, the concentration of VAP in plasma, and the levels of cAMP, MDA, SOD, GSH-Px in right cochlea were measured using spectrophotometric method. The V2R, NMDAR1, p-NMDAR1, AQP2, p-AQP2, caspase3/9 and c-caspase3/9 expressions in right cochlea were detected using western blot analysis.

Genome-wide DNA methylation analysis of human peripheral blood reveals susceptibility loci of diabetes-related hearing loss.

Diabetes-related hearing loss (DRHL) is a complication of diabetes mellitus that is drawing more attention currently. DNA methylation has a critical role in the pathogenesis of type 2 diabetes mellitus (T2DM) and its complications. Therefore, we investigated the genome-wide DNA methylation of peripheral blood of T2DM patients with/without hearing loss in order to explore the susceptibility loci of DRHL.

[Clinical analysis of 28 patients with chronic rhino-sinusitis only characterized olfactory disorders].

Objective: To analyses the clinical characteristics of 28 chronic rhino-sinusitis patients only characterized olfactory disorders.

Method: Twenty-eight patients who have only olfactory disorder were diagnosed chronic rhino-sinusitis, among which 16 patients accepted intranasal budesonide for 15 days. All patients accepted CT scan, T&T test and olfactory event-related potentials test before and after treatment.

[MRI features of olfactory bulb volume in healthy middle and old-aged persons.].

Objective: To investigate the differences of olfactory bulb (OB) volumes between younger and older, male and female, left-side and right-side in healthy middle and old-aged persons by MRI.

Methods: Ninety five healthy middle and old-aged volunteers (male:female = 45:50) were divided into 2 groups, group one included persons aged from 50 to 69, group two included persons elder than 70. The left-side, right-side and both-side volumes of OB, the volumes of brain and the ratio of OB/brain were measured by MRI.