Dibenzofurans from and their lipid-lowering activity.

Three new dibenzofurans, 2-hydroxy-3,4-dimethoxydibenzofuran (), 2,8-dihydroxy-3,4,9-trimethoxydibenzofuran () and 2-hydroxy-3,4,6,8-tetramethoxydibenzofuran (), together with three known dibenzofurans 1-hydroxy-2,3,4-trimethoxydibenzofuran (), 2-hydroxy-3,4,6-trimethoxydibenzofuran () and 1,6-dihydroxy-2,3,4-trimethoxydibenzofuran (), were isolated from the twigs and leaves of . Their structures were identified by the comprehensive analyses of the physicochemical properties and spectroscopic data (NMR and HR-ESI-MS). Compounds showed significant lipid-lowering activities, especially compound was stronger than simvastatin.

Phloridzin Highly Accumulated in Malus rockii Rehder and Its Structure Revision and Hypolipidemic Activity.

Phloridzin is a lead compound of the prestigious antidiabetic gliflozins. The present study found that phloridzin highly accumulated in Rehder. The content of phloridzin in was the highest among wild plants, with the percentage of 15.

A Facile Flow-Casting Production of Bioactive Glass Coatings on Porous Titanium for Bone Tissue Engineering.

Additive manufacturing enabled the fabrication of porous titanium (PT) with customized porosity and mechanical properties. However, functionalization of PT surfaces with bioactive coatings is being challenged due to sophisticated geometry and highly porous structure. In this study, a facile flow-casting technique was developed to produce homogeneous 45S5 bioactive glass (BG) coatings on the entire surface of PT.