Personalizing symptom monitoring and contact tracing efforts through a COVID-19 web-app.

Background: The Coronavirus Disease 2019 (COVID-19) pandemic has sparked attention in many countries, especially those that have experienced a steep spike in the number of identified cases. The continued spread of the coronavirus suggests that this situation may be here to stay for a while. Contact tracing is a time-consuming and resource-intensive process, which taps on the already lean healthcare resource in certain countries.

Three-component difunctionalization of alkenes leading to β-acetamido sulfides and β-acetoxy sulfides.

A novel method for the synthesis of β-acetamido sulfides via NBS-mediated aminosulfenylation of alkenes with thiophenols and nitriles under metal-free conditions has been described. And β-acetamido sulfides were also synthesized with 1-(arylthio)pyrrolidine-2,5-diones as substrates and HBr as an additive. On the other hand, iodine-catalyzed 1,2-acetoxysulfenylation of alkenes by using (diacetoxyiodo)benzene as an oxygen source to synthesise various β-acetoxy sulfides was described as well.