Objectives: To investigate the significance of proton magnetic resonance spectroscopy (H-MRS) and glutamate chemical exchange saturation transfer (Glu-CEST) techniques in assessing the condition and prognosis of acute bilirubin encephalopathy patients and to understand the mechanism of nerve injury in this disease.
Materials And Methods: From September 2019 to February 2021, 31 neonates with acute bilirubin encephalopathy and 16 healthy neonates were enrolled in this study. All the quantitative results of H-MRS, Glu-CEST, and conventional magnetic resonance imaging (MRI) of all neonates were analyzed.
Objectives: To evaluate the diagnostic and prognostic values of glutamate chemical exchange saturation transfer (GluCEST) magnetic resonance imaging as a quantitative method for pathogenetic research and clinical application of carbon monoxide (CO) poisoning-induced encephalopathy combined with the proton magnetic resonance spectroscopy (H-MRS) and the related histopathological and behavioral changes.
Methods: A total of 63 Sprague-Dawley rats were randomly divided into four groups. Group A ( = 12) was used for animal modeling verification; Group B ( = 15) was used for magnetic resonance molecular imaging, Group C ( = 15) was used for animal behavior experiments, and Group D ( = 21) was used for histopathological examination.
The abnormal T1-weighted imaging of MRI can be used to characterize neonatal acute bilirubin encephalopathy (ABE) in newborns, but has limited use in evaluating the severity and prognosis of ABE. This study aims to assess the value of diffusion kurtosis imaging (DKI) in detecting ABE and understanding its pathogenesis. Seventy-six newborns with hyperbilirubinemia were grouped into three groups (mild group, moderate group, and severe group) based on serum bilirubin levels.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2021
Rationale: The prevalence of ectopic thyroid is extremely low, with the condition observed in approximately 1 in 100,000 to 300,000 people. Thyroid gland ectopia develops as a result of the presence of developmental abnormalities during the migration of the thyroid anlage from the floor of the primitive foregut to its final position in the neck. Ectopic thyroid tissue is commonly observed in the lingual region, but can also present in other head and neck regions, as well as regions located at a large distance from the neck.
View Article and Find Full Text PDF