Endocrine disruptors and bladder function: the role of phthalates in overactive bladder.

Background: Phthalates, widely used as plasticizers, are pervasive environmental contaminants and endocrine disruptors. Their potential role in overactive bladder (OAB) pathogenesis is underexplored, necessitating further investigation into their impact on OAB using large-scale epidemiological data.

Methods: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2018.

Association between composite dietary antioxidant index and erectile dysfunction: a cross-sectional study from NHANES.

Background: Individual antioxidants may not fully capture the comprehensive antioxidant intake from an individual's diet. This study utilizes the Complex Dietary Antioxidant Index (CDAI) to evaluate the combined effects of various dietary antioxidants in the diet. The goal is to investigate the relationship between CDAI and the incidence of erectile dysfunction (ED), offering insights for dietary guidelines and intervention strategies aimed at mitigating the burden of ED.

Vitrectomy Combined with Internal Limiting Membrane Peeling for the Treatment of Hemorrhagic Retinal Arterial Macroaneurysm with "Multilayered" Hemorrhages.

Aims: To report clinical outcomes of pars plana vitrectomy combined with internal limiting membrane (ILM) peeling in the treatment of "multilayered" hemorrhages caused by hemorrhagic retinal arterial microaneurysm (RAM) in three cases.

Methods: Three patients with hemorrhagic RAM were reviewed. All patients underwent vitrectomy combined with ILM peeling.

Dynamic Non-Covalent Bonds Powering Enhanced Temporary Shape Retention Temperature and Mechanical Robustness in Shape Memory Polyurethane.

Shape memory polyurethane (SMPU) with excellent mechanical properties holds significant application value in engineering. However, achieving high strength and toughness typically relies on hydrogen bonding for energy dissipation, which limits the application of such PUs due to their deformation temperature being below room temperature. Here, we introduce a rigid long-chain polyamide acid with a rich aromatic structure as a chain extender, combined with metal coordination, to develop a shape memory polyurethane with a phase transition temperature of 50 °C and outstanding mechanical performance.

Bidirectional influence between benign prostatic hyperplasia, prostate cancer, and prostatitis and mental disorders: two-sample and multivariate mendelian randomization analyses.

Background: We aimed to use Mendelian randomization (MR) to determine the causality between fifteen major mental disorders (MDs) and benign prostatic hyperplasia (BPH), prostate cancer (PCa), and prostatitis.

Methods: The main MR analysis was performed using the inverse variance-weighted (IVW) method.

Results: The study found that insomnia (odds ratio [OR], 1.

Effect of antidepressants on ejaculation dysfunction in patients with depression and anxiety: A systematic review and network meta-analysis.

Introduction: Antidepressants may lead to a series of sexual adverse effects (SAEs), among which ejaculation dysfunction (EjD) is often overlooked by clinicians. The purpose of the present network meta-analysis was to assist drug adjustment by comparing and ranking the incidence of EjD among various antidepressants.

Methods: Relevant studies were retrieved from PubMed, Embase, Scopus, Web of Science, ClinicalTrials.

Identification of autophagy-related genes ATG18 subfamily genes in potato ( L.) and the role of gene in heat stress.

Autophagy is a highly conserved process in eukaryotes that is used to recycle the cellular components from the cytoplasm. It plays a crucial function in responding to both biotic and abiotic stress, as well as in the growth and development of plants. Autophagy-related genes (ATG) and their functions have been identified in numerous crop species.

Exploring the Adaptability of 4D Printed Shape Memory Polymer Featuring Dynamic Covalent Bonds.

4D printing (4DP) of high-performance shape memory polymers (SMPs), particularly using digital light processing (DLP), has garnered intense global attention due to its capability for rapid and high-precision fabrication of complex configurations, meeting diverse application requirements. However, the development of high-performance dynamic shape memory polymers (DSMPs) for DLP printing remains a significant challenge due to the inherent incompatibilities between the photopolymerization process and the curing/polymerization of high-strength polymers. Here, a mechanically robust DSMP compatible is developed with DLP printing, which incorporates dynamic covalent bonds of imine linking polyimide rigid segments, exhibiting remarkable mechanical performance (tensile strength ≈41.

Diet Quality at 3 Years of Age Relates to Lower Body Mass Index but Not Lower Blood Pressure at 10 Years of Age.

A healthy diet prevents overweight problems and hypertension. We investigated the associations of a healthy diet with the body mass index (BMI) and blood pressure (BP) in early childhood. In the GECKO birth cohort, height, weight, and BP were measured at 5 and 10 years of age.

Ultratough Supramolecular Polyurethane Featuring an Interwoven Network with Recyclability, Ideal Self-Healing and Editable Shape Memory Properties.

Developing multifunctional polymers with excellent mechanical properties, outstanding shape memory characteristics, and good self-healing properties is a formidable challenge. Inspired by the woven cross-linking strategy, a series of supramolecular polyurethane (PU) with an interwoven network structure composed of covalent and supramolecular cross-linking nodes have been successfully synthesized by introducing the ureido-pyrimidinone (UPy) motifs into the PU skeleton. The best-performing sample exhibited ultrahigh strength (∼77.

Super-Durable, Tough Shape-Memory Polymeric Materials Woven from Interlocking Rigid-Flexible Chains.

Developing advanced engineering polymers that combine high strength and toughness represents not only a necessary path to excellence but also a major technical challenge. Here for the first time a rigid-flexible interlocking polymer (RFIP) is reported featuring remarkable mechanical properties, consisting of flexible polyurethane (PU) and rigid polyimide (PI) chains cleverly woven together around the copper(I) ions center. By rationally weaving PI, PU chains, and copper(I) ions, RFIP exhibits ultra-high strength (twice that of unwoven polymers, 91.

Associations of insulin sensitivity and immune inflammatory responses with child blood lead (Pb) and PM exposure at an e-waste recycling area during the COVID-19 lockdown.

Fine particular matter (PM) and lead (Pb) exposure can induce insulin resistance, elevating the likelihood of diabetes onset. Nonetheless, the underlying mechanism remains ambiguous. Consequently, we assessed the association of PM and Pb exposure with insulin resistance and inflammation biomarkers in children.

Associations of co-exposure to polycyclic aromatic hydrocarbons and lead (Pb) with IGF1 methylation in peripheral blood of preschool children from an e-waste recycling area.

Background: Childhood exposure to polycyclic aromatic hydrocarbons (PAHs) or lead (Pb) is associated with epigenetic modifications. However, the effects of their co-exposures on IGF1 (Insulin-like growth factor 1) methylation and the potential role in child physical growth are unclear.

Methods: From our previous children study (N = 238, ages of 3-6), 75 children with higher total concentrations of urinary ten hydroxyl PAH metabolites (∑OH-PAHs) from an e-waste recycling area, Guiyu, and 75 with lower ∑OH-PAHs from Haojiang (reference area) were included.

responds to heat stress by regulating potato growth, photosynthesis, and antioxidant defenses.

Backgrounds: As a conserved signaling pathway, mitogen-activated protein kinase (MAPK) cascade regulates cellular signaling in response to abiotic stress. High temperature may contribute to a significant decrease in economic yield. However, research into the expression patterns of family genes under high temperature is limited and lacks experimental validation regarding their role in supporting potato plant growth.

Strengthening-Durable Trade-Off and Self-Healing, Recyclable Shape Memory Polyurethanes Enabled by Dynamic Boron-Urethane Bonds.

Addressing the demand for integrating strength and durability reinforcement in shape memory polyurethane (SMPU) for diverse applications remains a significant challenge. Here a series of SMPUs with ultra-high strength, self-healing and recyclability, and excellent shape memory properties through introducing dynamic boron-urethane bonds are synthesized. The introducing of boric acid (BA) to polyurethane leading to the formation of dynamic covalent bonds (DCB) boron-urethane, that confer a robust cross-linking structure on the SMPUs led to the formation of ordered stable hydrogen-bonding network within the SMPUs.

Tribological and Mechanochemical Properties of Nanoparticle-Filled Polytetrafluoroethylene Composites under Different Loads.

For the tribological properties of nanoparticle-modified PTFE, a more comprehensive study has been conducted, but there is still some room for research on tribology behavior, tribofilm formation and structure evolution of polytetrafluoroethylene (PTFE) filled with α-AlO and SiO nanoparticles during sliding against steel counterparts under different loads. At the same time, it establishes the linkage and mechanism between the maintenance of mechanical strength and the tribological application of polymers in service and provides corresponding scientific data and theoretical guidance for the long-lasting application of polymer lubrication materials. It is found that both composites exhibit good wear resistance across the pressure of 1 MPa to 10 MPa, with the α-AlO/PTFE composite demonstrating better performance stability compared to the SiO/PTFE composite.

Tribological Properties of Polyimide Composites Modified with Diamondoid Metal-Organic Frameworks.

In this work, diamondoid metal-organic frameworks (MOFs) were efficiently prepared by sonochemical synthesis and grown on polyimide (PI), aiming to improve the anti-wear performance of the PI matrix. By introducing MOFs into the PI matrix, the free movement of PI molecular chains were restricted, and its hardness and elastic modulus were improved. It was found that the wear rate of the 3 wt.

Controllable fabrication of CoNi bimetallic alloy for high-performance electromagnetic wave absorption.

With the coming era of artificial intelligence (AI) dominated by high-tech electronics, developing high-performance microwave absorption materials (MAMs) is imperative to solve the problem of increasing electromagnetic inference and pollution. Herein, a metal-organic framework (MOF)-derived CoNi bimetallic alloy (CoNi/C) with an irregular rod-like structure is prepared by a thermal reduction method. Introducing the CoNi alloy facilitates the balance between conduction loss and polarization loss and forms good impedance matching, leading to excellent microwave absorption performance.

Identification and molecular characterization of a novel totivirus from Mangifera indica.

In this study, we determined the complete genome sequence of a novel totivirus, tentatively named "Mangifera indica totivirus 1" (MiTV1), identified in 'Apple' mango in China. The double-stranded RNA genome of MiTV1 is 4800 base pairs (bp) in length and contains two open reading frames (ORFs) encoding a putative coat protein (CP) and an RNA-dependent RNA polymerase (RdRp). Phylogenetic analysis based on RdRp and CP amino acid sequences showed that MiTV1 is closely related to members of the genus Totivirus in the family Totiviridae.

An updated systematic review and meta-analysis of the effects of testosterone replacement therapy on erectile function and prostate.

Introduction: Testosterone replacement therapy (TRT) is a generally accepted method treating for aging-related late-onset hypogonadism (LOH). However, the efficacy and safety of TRT remain controversial. An updated systematic review and meta-analysis aimed to determine the effectiveness and security of TRT treating for LOH.

Upregulation of CCNB2 and a novel lncRNAs-related risk model predict prognosis in clear cell renal cell carcinoma.

Background: Clear cell renal cell carcinoma (ccRCC) is the main type of renal cell carcinoma. Cyclin B2 (CCNB2) is a subtype of B-type cyclin that is associated with the prognosis of several cancers. This study aimed to identify the relationship between CCNB2 and progression of ccRCC and construct a novel lncRNAs-related model to predict prognosis of ccRCC patients.