Effect of high welding heat input on the microstructure and low-temperature toughness of heat affected zone in magnesium-treated EH36 steel.

In the present study, the welding thermal cycle of magnesium-treated EH36 steel was simulated by a thermal simulation experiment machine. The effects of welding heat input on the microstructure and low temperature toughness of the welded joint were studied, and the mechanism of acicular ferrite nucleation induced by inclusion was revealed. The results showed that, when the welding heat input of 150 kJ/cm, 250 kJ/cm and 350 kJ/cm was utilized, the microstructure of heat affected zone in the experimental EH36 steel consisted of grain boundary ferrite, acicular ferrite, granular bainite, and a small amount of pearlite, but the volume fraction and grain size of each independent microstructure were different.

Evolution of inclusions in DH36 grade ship plate steel during high heat input welding.

In this paper, the solid solution and precipitation behavior of inclusions on the surface and 1/2 thickness of the tested steel plate under the condition of welding heat input of 400 kJ/cm is investigated by using laser confocal experiments with hot-rolled state DH36 ship plate steel as the research object, and the mechanism of the effect of inclusions on the phase transformation of an acicular ferrite is revealed. The results show that the inclusions of the tested steel are mainly composed of Oxide-MnS, MnS, Oxide, TiN, Spinel, etc. The amount of inclusions on the surface of the tested steel plate is significantly higher than that at the 1/2 thickness position.

The Influence of the Second Phase on the Microstructure Evolution of the Welding Heat-Affected Zone of Q690 Steel with High Heat Input.

Q690 steel is widely used as building steel due to its excellent performance. In this paper, the microstructure evolution of the heat-affected zone of Q690 steel under simulated high heat input welding conditions was investigated. The results show that under the heat input of 150-300 kJ/cm, the microstructures of the heat-affected zone are lath bainite and granular bainite.

Ginsenoside ompound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ.

Alzheimer's disease (AD) is the most common neurodegenerative condition worldwide, with amyloid (Aβ) fibrils presenting as its main pathological feature. This study investigated whether Ginsenoside Compound K (CK) has activity against Aβ and its mechanism in reducing synaptic damage and cognitive impairment. The binding capacity of CK to Aβ42 and Nrf2/Keap1 was determined using molecular docking.

Protective Effect of Shengmaiyin in Myocardial Hypertrophy-Induced Rats: A Genomic Analysis by 16S rDNA.

Background: The gut-cardiac axis theory provides new insights into the complex mechanisms of cardiac hypertrophy and provides new therapeutic targets. Cardiac hypertrophy is a risk factor for heart failure. Shengmaiyin (SMY) is a traditional Chinese medicine formula with clear effects in the treatment and prevention of cardiac hypertrophy, but the mechanism by which it improves cardiac hypertrophy is still unclear.

Investigating the Mechanism of Shengmaiyin () in the Treatment of Heart Failure Based on Network Pharmacology.

Background And Objective: To explore the molecular mechanism by which Shengmaiyin (Codonopsis pilosula) (SMY) improves isoproterenol (ISO)-induced heart failure (HF) in rats via a traditional Chinese medicine (TCM) integrated pharmacology research platform, The Chinese Medicine Integrated Pharmacology Platform (TCMIP V2.0).

Method: The chemical constituents and drug targets of SMY medicines were identified through TCMIP, and HF disease target information was collected.

The anti-aging effect of velvet antler polypeptide is dependent on modulation of the gut microbiota and regulation of the PPARα/APOE4 pathway.

We investigated the anti-aging effects of velvet antler polypeptide on D-galactose (D-gal)-induced aging mice. D-gal-induced aging mice were established and randomly divided into five groups, the control, model, vitamin E (VE), velvet antler polypeptide low-dose and velvet antler polypeptide high-dose groups. The Morris water maze test was used to evaluate the learning and memory abilities of aging mice.

Characterization and phylogenetic analysis of the complete chloroplast genome of (Amaranthaceae).

is an important medicinal herb. In this study, the complete chloroplast genome (plastome) of was repotred. It was a circular molecular of 150,452 bp in length and consists of a large single-copy region (LSC, 83,832 bp), a small single-copy region (SSC, 17,914 bp), and two inverted repeats (IRs, 24,353 bp for each) regions.