Publications by authors named "Qihang Cao"

Mycoplasmal pneumonia in sheep and goats usually result covert but huge economic losses in the sheep and goat industry. The disease is prevalent in various countries in Africa and Asia. Clinical manifestations in affected animals include anorexia, fever, and respiratory symptoms such as dyspnea, polypnea, cough, and nasal discharge.

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Background And Aim: The purpose of the current study was to investigate the predictive value of hepatitis B core-related antigen (HBcrAg) on the occurrence and recurrence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB).

Methods: We searched PubMed, Embase, Scopus, and Web of Science from database inception to April 6, 2023. Pooled hazard ratio (HR) or odds ratio (OR) with 95% confidence interval (CI) was calculated for the occurrence and recurrence of HCC.

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We describe a nickel-catalyzed carbonylative cross-coupling of unactivated secondary alkyl electrophiles with the organozinc reagent at atmospheric CO gas, thus allowing the expedient construction of unsymmetric dialkyl ketones with broad functional group tolerance. The leverage of a newly developed -pincer type ligand enables the chemoselective three-component carbonylation by overcoming the competing Negishi coupling, the undesired β-hydride elimination, and dehalogenation of alkyl iodides side pathways. Both alkyl iodides and alkyl tosylates are compatible in the single electron transfer involved mechanism.

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The community of microorganisms known as gut microbiota that lives in the intestine confers significant health benefits on its host, primarily in the form of immunological homeostasis regulation. Gut microbiota not only can shape immune responses in the gut but also in other organs. This review focus on the gut-lung axis.

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A cost-effective and sustainable method is successfully developed to produce lignin-based cryogels with a mechanically robust 3D interconnected structure. A choline chloride-lactic acid (ChCl-LA)-based deep eutectic solvent (DES) is used as a cosolvent to promote the synthesis of lignin-resorcinol-formaldehyde (LRF) gels that can self-assemble a robust string-bead-like framework. The molar ratio of LA to ChCl in DES has a significant influence on the gelation time and properties of the ensuing gels.

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is a widespread foodborne pathogen contaminating foods during their production or processing stages. Fresh meat is susceptible to such contamination if it is not properly preserved. Our study was conducted to reveal the level of contamination and prevalence of spp.

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Biofilm (BF) formation is a considerable obstacle to the effective control of (LM). In this study, we used transcriptomics to analyze LM BF and planktonic bacteria at different stages of BF formation and growth to compare differential gene expression between the 2. We identified 1588, 1517, and 1462 differentially expressed genes (DEGs) when early formation BF and planktonic bacteria were compared at 12, 24, and 48 h, respectively.

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In order to clarified characteristics and function of internalin G (inlG) in ATCC19111 (1/2a) (LM), the immune protection of the inlG was evaluated in mice, the homologous recombination was used to construct deletion strains, and their biological characteristics were studied by the transcriptomics analysis. As a result, the immunization of mice with the purified protein achieved a protective effect against bacterial infection. The deletion strain LM-AinlG was successfully constructed with genetic stability.

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The detection of a small number of exosomes provides the possibility for early cancer diagnosis and prognosis. Here, a multi-signal amplified electrochemical sensing platform was explored for the ultrasensitive detection of tumor exosomes relying on catalytic hairpin assembly-triggered DNA walker, entropy beacon-based DNA assembly and Ag@C core-shell nanocomposites. In this work, the utilization of Ag@C nanocomposites as electrode interface effectively enhanced functional active sites and electron transfer capability.

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Article Synopsis
  • This study presents a new DNA walking machine that uses aptamers to recognize and bind to exosomes.
  • The machine enables sensitive detection of exosomes using electrochemiluminescence (ECL) techniques.
  • This research showcases a novel approach for detecting exosomes, which could have important implications in biomedical applications.
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