Publications by authors named "Qide Liu"
Article Synopsis
- The QAMS method was developed to simultaneously measure 18 active components in C. J. Tseng using HPLC and specific internal reference substances.
- The study evaluated the accuracy of the QAMS method, finding that the concentration of analytes and curve intercepts significantly influence the results, with different effects seen in linear regression compared to average methods.
- Various chemometric techniques, including HCA, PCA, and SA, were used to classify samples based on the marker compounds, yielding consistent findings with the quantitative results.
[Toxicokinetics and tissue distribution study of arsenic in realgar].
Zhongguo Zhong Yao Za Zhi
July 2010
Objective: To study the toxicokinetics and tissue distribution of total arsenic after giving different doses realgar to rats.
Method: The concentration of arsenic in blood, urine and main organs were determined after single oral administration of 3.738, 1.
Objective: To observe the effects of Rhizoma Zingiberis and Pericarpium Citri Reticulatae extracts on acute myocardial ischemia rats and explore the mechanism.
Methods: The model of myocardial ischemia in rats was established by ligating the front descending anterior branch of the coronary artery. With Fufang Danshen Pill as positive control drug,the effects of Rhizoma Zingiberis and Pericarpium Citri Reticulatae extracts on the electrocardiogram (ECG), the extension of myocardial infarction, the hemorheology indexes, lactic dehydrogenase (LDH), creatine kinase (CK), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) in rats were evaluated.
[Preparation of the oral self-microemulsifying drug delivery system of GBE50].
Yao Xue Xue Bao
July 2009
To prepare the oral self-microemulsifying drug delivery system (SMEDDS) of GBE50, balance solubility method was used to screen emulsifier and assistant emulsifier; a pseudo-tamary phase diagram was used to prepare microemulsion; and orthogonal design was used to optimize formulation. Self-microemulsifying efficiency, dissolution, stability and pharmacokinetics of the preparation were studied. As a result, GBE50-SMEDDS of IPM, Cremophor EL, 1,2-propanediol and GBE50 could be self emulsified to form stable microemulsion with particle diameter between 20 and 50 nm when emulsifying with water.
View Article and Find Full Text PDFObjective: To observe the therapeutic effect of Wuling Powder extract on rats with renal hypertension and to evaluate the influence of it on the volume of urine and the concentrations of Na(+), K(+), Cl(-).
Methods: Reformed Gold-blatt hypertension rat model (G-2K1C) was established. The rats were divided into 6 groups as follows: sham-operation group; model group, Wuling Powder high dosage group (80 g/kg), Wuling Powder middle dosage group (40 g/kg), Wuling Powder low dosage group (20 g/kg), and hydrochlorothiazide (HCT) group (25 mg/kg).