MSDEnet: Multi-scale detail enhanced network based on human visual system for medical image segmentation.

In medical image segmentation, accuracy is commonly high for tasks involving clear boundary partitioning features, as seen in the segmentation of X-ray images. However, for objects with less obvious boundary partitioning features, such as skin regions with similar color textures or CT images of adjacent organs with similar Hounsfield value ranges, segmentation accuracy significantly decreases. Inspired by the human visual system, we proposed the multi-scale detail enhanced network.

Mesenchymal Stem Cells Accelerate Recovery of Acetic Acid-Induced Chronic Gastric Ulcer by Regulating Ekt/Akt/TRIM29 Axis.

Chronic gastric ulcer (CGU), a prevalent digestive disease, has a high incidence and is seriously harmful to human health. Mesenchymal stem cells (MSCs) have been proven to have beneficial therapeutic effects in many human diseases. Here, a CGU model induced by acetic acid in mice was used to evaluate the repair effects and potential mechanism of human umbilical cord-derived MSCs (hUC-MSCs) and hUC-MSCs derived conditioned medium (hUC-MSC-CM).

Composite Neighbor-Aware Convolutional Metric Networks for Hyperspectral Image Classification.

Supervised classification of hyperspectral image (HSI) is generally required to obtain better performance in spectral-spatial feature learning by fully using complex pixel- and superpixel-level interdependencies with small labeled samples. Limited by the local regular convolutions, convolutional neural networks (CNNs) can only exploit information from the short-range Euclidean neighbors of a target, hindering the effectiveness of feature representation. In contrast, graph convolutional networks (GCNs) can learn long-range dependencies between non-Euclidean neighbors but usually require the input of a full graph constructed from a whole HSI, making GCNs must be trained in a full-batch manner with tremendous computational consumption.

Semiconducting two-dimensional group VA-VA haeckelite compounds with superior carrier mobility.

A series of two-dimensional (2D) single-layer binary group VA-VA crystals, where VA represents P, As, Sb and Bi, are explored by the first-principles calculations. Unlike the orthorhombic α-phase and hexagonal β-phase, these crystals have a tetragonal haeckelite lattice and are named as T-VA-VAs. These ultrathin 2D materials have high thermal stability and are semiconductors with moderate band gaps ranging from 0.

In vitro photodynamic therapy of endothelial cells using hematoporphyrin monomethyl ether (Hemoporfin): Relevance to treatment of port wine stains.

Hemoporfin (hematoporphyrin monomethyl ether, HMME) is a relatively new photosensitizer that has achieved success in mediating photodynamic therapy (PDT) of port wine stains in China. However, the exact mechanism of Hemoporfin PDT on endothelial cell proliferation and apoptosis is unclear. The present study investigated the mechanism of action of HMME-PDT on endothelial cells in vitro.

CT-721, a Potent Bcr-Abl Inhibitor, Exhibits Excellent and Efficacy in the Treatment of Chronic Myeloid Leukemia.

Kinase inhibitors that target Bcr-Abl are highly effective in the treatment of chronic myeloid leukemia (CML). However, these inhibitors are often invalidated due to the drug resistance. Therefore, the discovery and development of novel Bcr-Abl inhibitors is required to overwhelm the drug resistance in the treatment of CML resistant to the currently used first-line Bcr-Abl inhibitors.

Development of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) polysaccharides injection formulation.

Biochemical and pharmacological research has demonstrated that Lingzhi or Reishi medicinal mushroom Ganoderma lucidum polysaccharides (GLPS) have significant anticancer, antitumor, and antioxidant activities. To investigate the effect of injecting GLPS into hosts for clinical studies, aqueous polysaccharide extracts from G. lucidum fruit bodies were purified by deproteinization using the Sevage method, anion-exchange chromatography elution (cellulose DEAE-52 chromatography), dialysis, ethanol precipitation, and active carbon and millipore membrane filtration techniques.

4-Allyl-2-meth-oxy-phenyl 3,4-dichloro-benzene-sulfonate.

The title compound, C(16)H(14)Cl(2)O(4)S, was obtained by the reaction of eugenol (4-allyl-2-meth-oxy-phenol) and 3,4-dichloro-benzene-sulfonyl chloride. The dihedral angle between the benzene rings in the mol-ecule is 40.53 (4)°.