Microwave-enhanced Fe/PDS system for treating refractory organic matter in biotreated landfill leachate effluent.

The effluent produced from treating landfill leachate via biological methods still contains a large amount of refractory organic matter and needs to be further treated. In this study, we used a microwave-enhanced zero-valent iron/peroxydisulfate (MW/Fe/PDS) system for the further treatment of biotreated landfill leachate effluent (BTLE). We investigated the efficiency and mechanism of removing refractory organic matter from BTLE.

Molecular composition of hydroxyl radical-resistant organics in municipal solid waste leachate.

Although hydroxyl radicals (OH) degrade organic pollutants nonselectively, their mineralization rate during the treatment of waste leachate biological treatment effluent (BTL) using Fenton or Fenton-like systems is not high, and the reason is unknown. In this study, we investigated three typical Fenton-like systems that act on dissolved organic matter (DOM) in BTL. We analyzed the molecular composition of DOM resistant to OH, using ultrahigh resolution mass spectrometry.

Molecular composition and formation mechanism of chlorinated organic compounds in biological waste leachate treated by electrochemical oxidation with a boron-doped diamond anode.

The use of electrochemical oxidation with boron-doped diamond (BDD) as an anode has been demonstrated to be an effective means of removing dissolved organic matter (DOM) from biologically treated waste leachate. However, in the presence of chloride ions, undesired chlorine evolution occurs on the anode; this forms chlorinated DOM, mostly of unknown molecular composition. We investigate the molecular composition and formation mechanism of chlorinated DOM during electrochemical oxidation process of biologically treated leachate DOM.

Insights into the hydrogenation reaction degradation mechanisms of lignin model compound using density functional theory methods.

Lignin through pyrolysis results in a liquid byproduct that contains a significant proportion of phenolic compounds, which can be subsequently enhanced into aromatic hydrocarbons using hydrogenation methods. To comprehend the reaction mechanism of the lignin hydrogenation process, we conducted theoretical investigations on the hydrogenation reaction process of different phenolic lignin model compounds by theoretical calculation method M06-2X/6-31++G(d,p). Different potential reaction routes were developed for the hydrogenation process of lignin model compounds, and the thermodynamic and kinetic properties of key reaction steps in each pathway were computed.

Sprayable biomimetic double mask with rapid autophasing and hierarchical programming for scarless wound healing.

Current sprayable hydrogel masks lack the stepwise protection, cleansing, and nourishment of extensive wounds, leading to delayed healing with scarring. Here, we develop a sprayable biomimetic double wound mask (BDM) with rapid autophasing and hierarchical programming for scarless wound healing. The BDMs comprise hydrophobic poly (lactide--propylene glycol--lactide) dimethacrylate (PLD) as top layer and hydrophilic gelatin methacrylate (GelMA) hydrogel as bottom layer, enabling swift autophasing into bilayered structure.

Destabilization mechanisms of Semi-aerobic aged refuse biofilters under harsh treatment conditions: Evidence from fluorescence and microbial characteristics.

Semi-aerobic aged refuse biofilters (SAARB) are commonly-used biotechnologies for treating landfill leachate. In actual operation, SAARB often faces harsh conditions characterized by high concentrations of chemical oxygen demand (COD) and Cl, as well as a low carbon-to-nitrogen ratio (C/N), which can disrupt the microbial community within SAARB, leading to operational instability. Maintaining the stable operation of SAARB is crucial for the efficient treatment of landfill leachate.

Nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of tofacitinib for treating alopecia areata.

Alopecia areata affects over 140 million people worldwide and causes severe psychological distress. The Janus kinase (JAK) inhibitor, tofacitinib, shows significant potential in therapeutic applications for treating alopecia areata; however, the systemic adverse effects of oral administration and low absorption rate at the target site limit its application. Hence, to address this issue, we designed topical formulations of tofacitinib-loaded cationic lipid nanoparticles (TFB-cNLPs) with particle sizes of approximately 200 nm.

Screening, characterization and mechanism of a potential stabiliser for nisin nanoliposomes with high encapsulation efficiency.

The encapsulation efficiency (EE%) reflects the amount of bioactive components that can be loaded into nanoliposomes. Obtaining a suitable nanoliposome stabiliser may be the key to improving their EE%. In this study, three polyphenols were screened as stabilisers of nanoliposomes with high nisin EE%, with curcumin nanoliposomes (Cu-NLs) exhibiting the best performance (EE% = 95.

Identification of as a Tumor Marker for Oral Squamous Cell Carcinoma.

Background: Kinesin family member 26B () has been closely linked to the occurrence and progression of various tumors. However, there is limited research on its role in oral squamous cell carcinoma (OSCC). This article aims to investigate the expression levels and mechanisms of in OSCC.

Insights into the hydrolysis/alcoholysis/ammonolysis mechanisms of ethylene naphthalate dimer using density functional theory (DFT) method.

Hydrolysis, alcoholysis and ammonolysis are viable routes for the efficient degradation and recycling of polyethylene naphthalate (PEN) plastic waste. Various possible hydrolysis/alcoholysis/ammonolysis reaction pathways for the degradation mechanism of the ethylene naphthalate dimer were investigated using the density functional theory (DFT) B3P86/6-31++G(d,p). To determine the thermodynamic and kinetic parameters, geometric structure optimization and frequency calculation were performed on a range of intermediates, transition states, and products associated with the reaction.

Preparation of PCL/lecithin/bacteriocin CAMT6 antimicrobial and antioxidant nanofiber films using emulsion electrospinning: Characteristics and application in chilled salmon preservation.

Multi-functional packaging materials are an important development for food preservation. Emulsion electrospinning is a novel and simple method that can be used to prepare multi-functional packaging materials, which can effectively protect the loaded active substances during the preparation process. In this study, PCL/lecithin/bacteriocin CAMT6 nanofiber films with antimicrobial and antioxidant activity were prepared by emulsion electrostatic spinning.

Molecular Characteristics and Formation Mechanisms of Unknown Ozonation Byproducts during the Treatment of Flocculated Nanofiltration Leachate Concentrates Using O and UV/O Processes.

Both ozone (O) and UV/O treatment processes can effectively remove organic matter in the flocculated membrane filtration concentrate from landfill leachate, but the ozonation byproducts (OBPs) generated in the processes remain unknown. Using electrospray ionization-coupled Fourier transform ion cyclotron resonance mass spectrometry (ESI FT-ICR MS), this study investigated the molecular characteristics of unknown OBPs and their formation mechanisms during the treatment of flocculated nanofiltration concentrate (FNFC) using the O and UV/O processes. The results showed that after being treated by the O and UV/O processes, the average value of the oxygen-to-carbon ratio (O/C) in the FNFC organic matter increased substantially from 0.

Molecular comparison of organic matter removal from shale gas flowback wastewater: Ozonation versus Fenton process.

Shale gas extraction process generates a large amount of shale gas flowback wastewater (SGFW) containing refractory organic compounds, which can pose serious environmental threats if not properly treated. However, the extremely complex compositions of organics in SGFW are still unknown and their transformation pathways in O- and OH-dominated systems are not well recognized, which restrain the selection of treatment technology and optimization of operational parameters. The removal characteristics and reaction mechanism of dissolved organic matter (DOM) in SGFW treated by ozonation and Fenton processes were comparatively investigated using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Polarized light compass decoding.

The brains of some insects can encode and decode polarization information and obtain heading angle information. Referring to the encoding ability of insects, exponential function encoding is designed to improve the stability of the polarized light compass artificial neural network. However, in the decoding process, only neurons with the largest activation degree are used for decoding (maximum value decoding), so the heading information contained in other neurons is not used.

Molecular-level transformation of refractory organic matter during flocculation-ultraviolet/peroxymonosulfate treatment of MBR-treated landfill leachate.

Refractory organic matter in membrane bioreactor effluent resulting from landfill leachate treatment has a complex composition. This paper identified the transformation mechanism of organic matter in a flocculation-ultraviolet (UV)/peroxymonosulfate (PMS) system at the molecular level using electrospray ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry. The results showed that the flocculation system was able to remove a large amount of dissolved organic matter (DOM) with high oxidation and unsaturation/saturation.

Preparation, characterization and application of bacteriocin CAMT6 nanoliposomes using resveratrol as a novel stabilizer.

Nanoliposomes are ideal nanocarriers for encapsulated active compounds used in the food industry as they provide stability and controlled release. However, cholesterol may pose risks in large intake, which is the commonly-used nanoliposome stabilizers. In this study, resveratrol was used instead of cholesterol as a novel nanoliposome stabilizer to construct a resveratrol blank liposome (RBL) system.

Enhanced performance and mechanism of the combined process of ozonation and a semiaerobic aged refuse biofilter for mature landfill leachate treatment.

A semiaerobic aged refuse biofilter (SAARB) can effectively treat mature landfill leachate (ML), but prolonged operation can lead to the enrichment of pollutants in the biofilter, resulting in severely degraded treatment performance. In this study, we constructed a combination process of ozonation and a SAARB to treat ML based on the principles of selective oxidation of aromatic organics by ozone and the preference of microorganisms for ozonation products. The results showed that the removal of organic and nitrogen pollutants became extremely poor after long-term treatment of ML using the SAARB alone.

Regional distribution, properties, treatment technologies, and resource utilization of oil-based drilling cuttings: A review.

Oil-based drilling cuttings (OBDC) are hazardous wastes produced during the extensive use of oil-based drilling mud in oil and gas exploration and development. They have strong mutagenic, carcinogenic, and teratogenic effects and need to be properly disposed of to avoid damaging the natural environment. This paper reviews the recent research progress on the regional distribution, properties, treatment technologies, and resource utilization of OBDC.

Effect of Wax Composition and Shear Force on Wax Aggregation Behavior in Crude Oil: A Molecular Dynamics Simulation Study.

To explore the influence of different wax components and the shear effect exerted by the pump and pipe wall in the process of crude oil pipeline transportation on the microbehavior of wax aggregation in crude oil at low temperatures, molecular dynamics models of binary and multivariate systems of crude oil with different wax components are established in this paper. The simulation results are compared with the existing experimental results and the NIST database to verify the rationality and accuracy of the models. By using the established binary model to simulate four crude oil systems containing different wax components, it can be found that the longer the wax molecular chain, the more easily the wax molecules aggregate.

Single-cell landscape reveals active cell subtypes and their interaction in the tumor microenvironment of gastric cancer.

Gastric cancer remains the third most common cause of cancer-related death worldwide. The development of novel therapeutic strategies for gastric cancer requires a deep understanding of the tumor cells and microenvironment of gastric cancer. We performed the single-cell RNA sequencing (scRNA-seq) on nine untreated non-metastatic gastric cancer patients.

Molecular insights into the transformation of refractory organic matter in landfill leachate nanofiltration concentrates during a flocculation and O/HO treatment.

During leachate treatment, molecular information regarding the completely removed, partially removed, less-reactive, increased, and produced parts of dissolved organic matter (DOM) remains unknown. This study applied ESI FT-ICR MS to investigate the transformation characteristics of leachate nanofiltration concentrate (NFC) DOM during a combined flocculation-O/HO process. The NFC contained 5069 compounds in four main classes (CHO, CHON, CHOS, and CHONS compounds).

The molecular differences of young and mature landfill leachates: Molecular composition, chemical property, and structural characteristic.

Landfill leachate is a highly contaminated and complex organic wastewater. It can be categorized into young (YL) and mature leachate (ML) based on the landfill age, with significant differences in the composition of organic matter, resulting from the significant differences in humification degree. To compare the organic composition of YL and ML, ESI FT-ICR MS was applied to systematically investigate their molecular composition, chemical properties, and structural characteristics.

Novel strategy for controlling colloidal instability during the flocculation pretreatment of landfill leachate.

Flocculation is an economical and effective pretreatment technology for landfill leachate. An iron salt flocculant is often used in landfill leachate pretreatment, but the flocs that are formed are affected by the operation sequence, which subsquently influences flocculation. This study selected three representative landfill leachates (i.