Perspective on Lewis Acid-Base Interactions in Emerging Batteries.

Lewis acid-base interactions are common in chemical processes presented in diverse applications, such as synthesis, catalysis, batteries, semiconductors, and solar cells. The Lewis acid-base interactions allow precise tuning of material properties from the molecular level to more aggregated and organized structures. This review will focus on the origin, development, and prospects of applying Lewis acid-base interactions for the materials design and mechanism understanding in the advancement of battery materials and chemistries.

Identification of Novel Tumor Pyroptosis-Related Antigens and Pyroptosis Subtypes for Developing mRNA Vaccines in Pancreatic Adenocarcinoma.

Background: As one of the important components of immunotherapies, mRNA vaccines have displayed promising clinical outcomes in solid tumors. Nonetheless, their efficacy remains unclear in pancreatic adenocarcinoma (PAAD). Given the interaction of pyroptosis with anticancer immunity, our study aims to identify pyroptosis-related antigens for mRNA vaccine development and discern eligible candidates for vaccination.

Sieving carbons promise practical anodes with extensible low-potential plateaus for sodium batteries.

Non-graphitic carbons are promising anode candidates for sodium-ion batteries, while their variable and complicated microstructure severely limits the rational design of high-energy carbon anodes that could accelerate the commercialization of sodium-ion batteries, as is the case for graphite in lithium-ion batteries. Here, we propose sieving carbons, featuring highly tunable nanopores with tightened pore entrances, as high-energy anodes with extensible and reversible low-potential plateaus (<0.1 V).

Partial omentectomy maybe practicable for T3 or shallower gastric cancer patients.

Background: Total omentectomy is often performed with gastrectomy as radical surgery for gastric cancer (GC) patients. However, it remains controversial whether GC patients can benefit from omentectomy. The aim of this study was to analyze the incidence and clinical significance of tumor deposits (TDs) in different anatomical subregions of perigastric omentum in GC patients undergoing gastrectomy with total omentectomy.

Serum lactate dehydrogenase as a novel prognostic factor for patients with primary undifferentiated pleomorphic sarcomas.

Purpose: Among soft tissue sarcomas, undifferentiated pleomorphic sarcoma (UPS) has relatively higher potential of recurrence and metastasis. As serum lactate dehydrogenase (LDH) is associated with tumor progression and unfavorable outcomes in multiple malignancies, we designed this study to explore the relationship between preoperative serum LDH and prognosis in UPS patients.

Methods: We extracted the data of UPS patients who underwent primary surgery in Shanghai Cancer Center, Fudan University.

How Is Cycle Life of Three-Dimensional Zinc Metal Anodes with Carbon Fiber Backbones Affected by Depth of Discharge and Current Density in Zinc-Ion Batteries?

Zinc (Zn) metal is an attractive anode material for aqueous Zn-ion batteries (ZIBs). Three-dimensional (3D) carbon frameworks may serve as lightweight and robust hosts to enable porous Zn electrodes with a long cycle life. However, Zn electrode tests under a low depth of discharge (DOD) and current density often yield unreliable promises.

A Protective Layer for Lithium Metal Anode: Why and How.

Lithium metal is the most promising candidate anode material for high energy density batteries, but its high activity and severe dendrite growth lead to safety concerns and limit its practical use. Constructing a protective layer (PL) on the lithium surface to avoid the side reactions and stabilize the electrode-electrolyte interface is an effective approach to solve these problems. In this review, the recent progress on PLs is summarized, and their desired properties and design principles are discussed from the aspects of materials selection and the corresponding fabrication methods.

Circ-PTPDC1 promotes the Progression of Gastric Cancer through Sponging Mir-139-3p by Regulating ELK1 and Functions as a Prognostic Biomarker.

Circular RNAs (circRNAs) is a novel class of non-coding RNAs resulting from the non-canonical splicing of linear pre-mRNAs. However, the role of circRNAs in gastric cancer (GC) remains indistinct. This study aims to explore their potential modulation in GC and its prognostic value.

A (110) Facet-Dominated Vanadium Dioxide Enabling Bidirectional Electrocatalysis for Lithium-Sulfur Batteries.

Catalysis is an effective way to improve the performance of lithium-sulfur (Li-S) batteries by enhancing the reaction kinetics of polysulfides. However, the bidirectional catalysis for discharging and charging processes in Li-S battery is still challenging. Herein, a (110) facet-dominated VO is prepared through the thermal-induced partial decomposition of (NH)VO (NVO), forming a (110)VO@NVO hybrid with the bidirectional catalysis ability.

High-performance lithium-sulfur batteries enabled by regulating LiS deposition.

Lithium-sulfur batteries (LSBs) have received intensive attention in recent years due to their high theoretical energy density derived from the lithiation of sulfur. In the discharge process, sulfur transforms into lithium polysulfides (LiPSs) that dissolve in liquid electrolytes and then into insoluble LiS precipitated on the electrode surface. The electronically and ionically insulating LiS leads to two critical issues, including the sluggish reaction kinetics from LiPSs to LiS and the passivation of the electrode.

Rich Heterointerfaces Enabling Rapid Polysulfides Conversion and Regulated LiS Deposition for High-Performance Lithium-Sulfur Batteries.

The practical uses of lithium-sulfur batteries are greatly restricted by the sluggish reaction kinetics of lithium polysulfides (LiPSs), leading to low sulfur utilization and poor cyclic stability. Using the heterostructure catalysts is an effective way to solve the above problems, but how to further enhance the conversion efficiency and avoid the surface passivation by the insulative LiS has not been well investigated. Herein, a heterostructure catalyst with rich heterointerfaces was prepared by modifying MoN microbelt with SnO nanodots.

Novel Nomograms-Based Prediction Models for Patients with Primary Undifferentiated Pleomorphic Sarcomas Resections.

Background: Undifferentiated pleomorphic sarcomas (UPS) were one of the most common soft tissue sarcomas. As UPS had relatively high potentials of recurrence and metastasis, we designed two nomograms to better predict the overall survival (OS) and time to recurrence (TTR) for patients who underwent primary surgery.

Methods: The data of UPS patients who underwent primary surgery were extracted from Shanghai Cancer Center, Fudan University.

Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma.

Background: Treating patients with advanced sarcomas is challenging due to great histologic diversity among its subtypes. Leiomyosarcoma (LMS) and de-differentiated liposarcoma (DDLPS) are two common and aggressive subtypes of soft tissue sarcoma (STS). They differ significantly in histology and clinical behaviors.

Surgical treatment strategies for extra-pelvic intravenous leiomyomatosis.

Background: Extra-pelvic intravenous leiomyomatosis (IVL) extending into inferior vena cava (IVC) or heart (i.e. intracardiac leiomyomatosis, ICL) is an extremely rare benign disease.

An interlayer composed of a porous carbon sheet embedded with TiO nanoparticles for stable and high rate lithium-sulfur batteries.

The shuttling of lithium polysulfides (LiPSs) in lithium-sulfur (Li-S) batteries results in low sulfur utilization and fast capacity decay, hindering their practical applications. Constructing an interlayer is an efficient way to block the LiPS shuttling, but maintaining a low Li ion diffusion resistance with such an interlayer is hard to achieve. Herein, a thin porous carbon nanosheet embedded with TiO2 nanoparticles (denoted PCNS-TiO2) was used to fabricate an interlayer on the separator, which effectively solves the above problem.

Tumor-associated tertiary lymphoid structure predicts postoperative outcomes in patients with primary gastrointestinal stromal tumors.

Tumor-infiltrating tertiary lymphoid structures (TLS) are thought to have anti-tumor activity and are believed to indicate a favorable prognosis in cancer patients. However, the prognostic value of TLS in gastrointestinal stromal tumors (GIST) is unknown. We evaluated the prognostic value of TLS using two independent GIST cohorts.

Clinicopathological and molecular characteristics of abdominal desmoid tumors in the Chinese population: A single-center report of 15 cases.

Desmoid tumors (DTs), derived from the abdomen, are a type of rare and aggressive borderline tumor exhibiting high recurrence and malignant potential. The aim of the present study was to investigate the clinicopathological and molecular characteristics of abdominal DT in a Chinese population and to provide clues for selecting the optimal treatment strategy for different types of abdominal DT. The clinicopathological data of 15 consecutive patients with DT was collected.

A Functionalized Carbon Surface for High-Performance Sodium-Ion Storage.

Sodium-ion batteries (SIBs) are promising for large-scale energy storage systems and carbon materials are the most likely candidates for their electrodes. The existence of defects in carbon materials is crucial for increasing the sodium storage ability. However, both the reversible capacity and efficiency need to be further improved.

A Reduced Graphene Oxide/Disodium Terephthalate Hybrid as a High-Performance Anode for Sodium-Ion Batteries.

As a promising candidate for large-scale energy storage systems, sodium-ion batteries (SIBs) are experiencing a rapid development. Organic conjugated carboxylic acid anodes not only have tailorable electrochemical properties but also are easily accessible. However, the low stability and electrical conductivity hamper their practical applications.

Effects of eicosapentaenoic acid and docosahexaenoic acid on chylomicron and VLDL synthesis and secretion in Caco-2 cells.

The present research was undertaken to determine the effects of EPA (20 : 5 n-3) and DHA (22 : 6 n-3) on chylomicron and VLDL synthesis and secretion by Caco-2 cells. Cells were incubated for 12 to 36 h with 400  μM OA, EPA, and DHA; then 36 h was chosen for further study because EPA and DHA decreased de novo triglycerides synthesis in a longer incubation compared with OA  (P < 0.01).

DHA inhibits protein degradation more efficiently than EPA by regulating the PPARγ/NFκB pathway in C2C12 myotubes.

This study was conducted to evaluate the mechanism by which n-3 PUFA regulated the protein degradation in C2C12 myotubes. Compared with the BSA control, EPA at concentrations from 400 to 600 µM decreased total protein degradation (P < 0.01).