To Investigate the Diagnostic Accuracy and Prognostic Value of Amplitude-Integrated Electroencephalography (aEEG) in Neonatal Hypoxic Ischemic Encephalopathy.

Objective: The objective of this study is to investigate the diagnostic accuracy and prognostic value of amplitude-integrated electroencephalography (aEEG) in neonatal hypoxic ischemic encephalopathy (HIE).

Methods: Fifty-three neonates with HIE admitted to our hospital from February 2020 to September 2021 were included in the encephalopathy group, while 22 healthy neonates born in our hospital during the same period were included in the healthy group. The neonates were separated into three subgroups based on their aEEG results: normal, slightly abnormal, and severely abnormal.

Phytosulfokine promotes fruit ripening and quality via phosphorylation of transcription factor DREB2F in tomato.

Phytosulfokine (PSK), a plant peptide hormone with a wide range of biological functions, is recognized by its receptor PHYTOSULFOKINE RECEPTOR 1 (PSKR1). Previous studies have reported that PSK plays important roles in plant growth, development, and stress responses. However, the involvement of PSK in fruit development and quality formation remains largely unknown.

Correction: The novel leucine-rich repeat receptor-like kinase MRK1 regulates resistance to multiple stresses in tomato.

[This corrects the article DOI: 10.1093/hr/uhab088.].

Glucose sensing by regulator of G protein signaling 1 (RGS1) plays a crucial role in coordinating defense in response to environmental variation in tomato.

Low light intensities affect the outbreak of plant diseases. However, the underlying molecular mechanisms remain poorly understood. High-performance liquid chromatography analysis of tomato (Solanum lycopersicum) revealed that apoplastic glucose (Glc) levels decreased in response to low light.

A novel leucine-rich repeat receptor-like kinase MRK1 regulates resistance to multiple stresses in tomato.

Leucine-rich repeat receptor-like kinases (LRR-RLKs) are ubiquitous in higher plants, which act as receptors of extracellular signals to trigger multiple physiological processes. However, the functions of the majority of LRR-RLKs remain largely unknown, especially in tomato (Solanum lycopersicum L.).

Ethylene response factors 15 and 16 trigger jasmonate biosynthesis in tomato during herbivore resistance.

Jasmonates (JAs) are phytohormones with crucial roles in plant defense. Plants accumulate JAs in response to wounding or herbivore attack, but how JA biosynthesis is triggered remains poorly understood. Here we show that herbivory by cotton bollworm (Helicoverpa armigera) induced both ethylene (ET) and JA production in tomato (Solanum lycopersicum) leaves.

High CO - and pathogen-driven expression of the carbonic anhydrase βCA3 confers basal immunity in tomato.

Atmospheric CO concentrations exert a strong influence on the susceptibility of plants to pathogens. However, the mechanisms involved in the CO -dependent regulation of pathogen resistance are largely unknown. Here we show that the expression of tomato (Solanum lycopersicum) β-CARBONIC ANHYDRASE 3 (βCA3) is induced by the virulent pathogen Pseudomonas syringae pv.

An Essential Role of Mitochondrial α-Ketoglutarate Dehydrogenase E2 in the Basal Immune Response Against Bacterial Pathogens in Tomato.

Plants intensely modulate respiration when pathogens attack, but the function of mitochondrial respiration-related genes in plant-bacteria interaction is largely unclear. Here, the functions of α-ketoglutarate dehydrogenase (α) E2 subunit and alternative oxidase () were investigated in the interaction between tomato and the virulent bacterial pathogen pv. DC3000 ().

Supine versus semi-Fowler's positions for tracheal extubation in abdominal surgery-a randomized clinical trial.

Background: Tracheal extubation is commonly performed in the supine position. However, in patients undergoing abdominal surgery, the supine position increases abdominal wall tension, especially during coughing and deep breathing, which may aggravate pain and lead to abdominal wound dehiscence. The semi-Fowler's position may reduce abdominal wall tension, but its safety and comfort in tracheal extubation have not been reported.

Role of ethylene biosynthesis and signaling in elevated CO-induced heat stress response in tomato.

This article unveiled that ethylene biosynthesis and signaling play a critical role in heat stress response of tomato plants under elevated CO Plant responses to elevated CO and heat stress are tightly regulated by an intricate network of phytohormones. Plants accumulate ethylene (ET), the smallest hormone, in response to heat stress; however, the role of ET and its signaling in elevated CO-induced heat stress response remains largely unknown. In this study, we found that transcript levels of multiple genes relating to ET synthesis, signaling, and heat shock proteins (HSPs) were induced by elevated CO (800 μmol mol) compared to ambient CO (400 μmol mol) in tomato leaves under controlled temperature conditions (25 °C).

Stomatal movements are involved in elevated CO -mitigated high temperature stress in tomato.

Climate changes such as heat waves often affect plant growth and pose a growing threat to natural and agricultural ecosystems. Elevated atmospheric CO can mitigate the negative effects of heat stress, but the underlying mechanisms remain largely unclear. We examined the interactive effects of elevated CO (eCO ) and temperature on the generation of the hydrogen peroxide (H O ) and stomatal movement characteristics associated with heat tolerance in tomato seedlings grown under two CO concentrations (400 and 800 µmol mol ) and two temperatures (25 and 42°C).

Thymosin β4 inhibits microglia activation through microRNA 146a in neonatal rats following hypoxia injury.

Neuroinflammation mediated by activated microglia plays a pivotal role in the pathogenesis of neurological disorders, including hypoxic injury of the developing brain. Thymosin β4 (Tβ4), the major G-actin-sequestering molecule, has an anti-inflammatory effect and has been used to treat various neurological diseases. However, the effect of Tβ4 on hypoxia-induced microglia activation in the developing brain remains unclear.

Transcatheter closure of congenital perimembranous ventricular septal defect in children using symmetric occluders: an 8-year multiinstitutional experience.

Background: Perimembranous ventricular septal defects (pmVSDs) are one of the most common forms of congenital cardiac malformation in children. Results of transcatheter pmVSD closure remain debatable, prompting the need for further evaluation with regard to the safety and efficacy of this procedure. The aim of the study was to analyze the safety, efficacy, and long-term follow-up data associated with transcatheter closure of pmVSDs in children using symmetric occluders.

Transcatheter closure of perimembranous ventricular septal defect in a patient with abnormal inferior vena cava return.

An 8-year-old boy with a 3.8 mm perimembranous ventricular septal defect (PmVSD) and abnormal inferior vena cava return was attempted cardiac catheterization to occlude the VSD. Through the right jugular vein and right femoral artery approach, an 8 mm Amplatzer VSD occluder was successfully deployed under fluoroscopic and echocardiographic guidance.

[Hyperbaric oxygen improves long-term learning-memory deficits and brain injury in neonatal rat with hypoxia-ischemia brain damage].

Objective: To investigate the effect of hyperbaric oxygen (HBO) on long-term learning-memory disabilities and brain injury induced by hypoxia-ischemia in neonatal rat.

Methods: In the study, eighteen rats aged seven days were divid into three groups: (1) sham-operated group (SHAM), (2) hypoxia-ischemia group (HIBD), (3) HBO-treated hypoxia-ischemia group (HIBD + HBO). In hypoxia-ischemia groups, left common carotid artery was ligated permanently on the seventh postnatal day, two hours after the procedure; hypoxia (92% nitrogen and 8% oxygen) was induced for 2 h.

[Optimal therapeutic window of hyperbaric oxygenation in neonatal rat with hypoxic-ischemic brain damage].

Objective: Hyperbaric oxygenation (HBO) is an attractive procedure that has been used in treatment of hypoxic-ischemic encephalopathy (HIE). However, depending on the HBO protocol, especially the time point of starting treatment of HBO, different and conflicting results were obtained. This study was undertaken to search for the optimal therapeutic window of ABO in neonatal rat with hypoxic-ischemic brain damage (HIBD).