Construction of a nomogram for personalized prediction of lower limb lymphedema risk after cervical cancer surgery.

Objective: This study aims to construct and evaluate an individualized nomogram for predicting the risk of lower limb lymphedema after cervical cancer surgery. Healthcare professionals can utilize line chart models to predict the probability of postoperative lower limb lymphedema in different patients, allowing for the early identification of high-risk patients and facilitating early prevention and treatment.

Methods: A retrospective study was conducted among 411 cervical cancer patients treated at our hospital from May 2021 to December 2023.

The Analysis of Transition Readiness of Adolescent Epilepsy Patients from Childhood to Adult from the Perspective of Disease Self-management: A Cross-sectional Study in Southwest China.

Objective: The objective of this study was to investigate the transition readiness of juvenile epilepsy patients during the transition period from childhood to adulthood and analyze the impact of patients' basic characteristics and self-management on their transition readiness.

Methods: A total of 376 adolescent epileptic patients were selected as research objects from 3A general hospitals located in Chongqing, Guizhou, and Yunnan respectively, and a 3A children's specialist hospital in Chongqing, Jiangxi from May 2021 to February 2022. The readiness for transition was assessed using a transition readiness questionnaire, and patients' self-management skills were evaluated using the Self-Management Scale for Epilepsy Patients.

Comparison of organic and synthetic amendments for poplar phytomanagement in copper and lead-contaminated calcareous soil.

Soil remediation can be achieved through organic and synthetic amendments, but the differences in the phytomanagement of trace metal-contaminated land are unclear. We conducted an outdoor microcosm experiment to simulate the effects of organic amendment citric acid and synthetic amendments EDTA and EGTA on poplar phytomanagement of copper (Cu)- and lead (Pb)-contaminated calcareous land at doses of 0, 1, 3, and 9 mmol kg. We found that soil-bioavailable Cu and Pb contents increased by 2.

Temporal changes of calcareous soil properties and their effects on cadmium uptake by wheat under wastewater irrigation for over 50 years.

Calcareous soil has a strong buffering capacity for neutralizing acid and stabilizing cadmium (Cd) because of the high calcium carbonate (CaCO) content. However, it is not clear whether the buffering capacity of calcareous soil can be maintained after long-term wastewater irrigation. We selected a typical area in western China that has been irrigated with wastewater for over 50 years to study the temporal changes of soil properties and their effects on Cd uptake by wheat.

Association of survival and genomic mutation signature with immunotherapy in patients with hepatocellular carcinoma.

Background: Current guidelines lack recommendations for the use of immunotherapy and immune-related biomarkers for hepatocellular carcinoma (HCC). We aim to provide reliable evidence of the association of survival with HCC immunotherapy and to demonstrate that genomic mutation signature could be an effective biomarker to predict immunotherapy efficacy of HCC patients.

Methods: We conducted a meta-analysis of 17 randomized trials with 2055 patients and an individual patient-level analysis of 31 patients.