The phosphatidylethanolamine-binding protein (PEBP) gene family exists in all eukaryote kingdoms, with three subfamilies: (FLOWERING LOCUS T)-like, (TERMINAL FLOWER 1)-like, and (MOTHER OF FT AND TFL1)-like. genes promote flowering, genes act as a repressor of the floral transition, and genes have functions in flowering promotion and regulating seed germination. We identified and characterized orthologs of the / gene family in petunia to elucidate their expression patterns and evolution.
View Article and Find Full Text PDFMulticomponent drug metabolism can be defined as a research area that, rather than pharmacokinetics and pharmacodynamics, is a concerted dynamic metabolic variation of one component in several other compounds circumstance with the interaction of transport protein and drug metabolizing enzymes, and the study of the dynamic course of multiple components must be simultaneously determined. By the use of multicomponent drug metabolism in the clinical pharmacy research of traditional Chinese medicine (TCM), it can become a useful tool with the integration of the overall dialectical method and the concrete molecular approach.
View Article and Find Full Text PDFObjective: To investigate the damage effect of different fractions from Polygonum multiflorum on normal human liver and liver cancer cells, in order to seek for fractions that can obviously kill cancer cells but have less impact on normal liver cells, and make a preliminary study on different mechanism of the two kinds of cells.
Method: P. multiflorum water-eluted fraction (RW), 50% ethanol-eluted fraction (R50) and 95% ethanol-eluted fraction (R95) were successively obtained from 70% ethanol extracts of P.