Analysis of serum NLR combined with intraoperative margin condition to predict the prognosis of cervical HSIL patients undergoing LEEP surgery.

Objective: This study analyzed the prognosis of patients with high-grade squamous intraepithelial lesion (HSIL) after loop electrosurgical excision procedure (LEEP) and elucidated the predictive value of neutrophil-to-lymphocyte ratio (NLR) and margin condition in relation to prognostic recurrence.

Methods: A total of 209 patients were included, with 46 cases in the recurrence/residual group, 156 cases in the no recurrence/residual group, and 7 cases lost to follow-up. General information, past history and comorbid underlying diseases, laboratory tests, and other relevant clinical information were compared between the two groups.

Comprehensive analysis of the differential expression profile of microRNAs in missed abortion.

To screen the key circulating microRNAs (miRNAs) involved in missed abortion (MA) and explore their role in MA process. We examined the miRNA profile from the serum of three MA patients and three early pregnancy induced abortion patients (controls) by next-generation sequencing. We analyzed the target genes of the differentially expressed (DE) miRNAs to analyze the function and pathway enrichment using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes, respectively.