Publications by authors named "Qiao-Yan Liang"
Article Synopsis
- Proficient mismatch repair (pMMR/MSS) colorectal cancers (CRCs) have distinct characteristics compared to deficient mismatch repair (dMMR/MSI-H) tumors, particularly in response to immune therapies.
- The study highlights that ASCL2 is overexpressed in pMMR/MSS CRCs, leading to a more stem-like tumor behavior and fewer immune cells infiltrating the tumors compared to dMMR/MSI-H types.
- Targeting ASCL2, combined with immune checkpoint inhibitors, shows promise as a potential treatment strategy for pMMR/MSS CRCs by promoting anti-tumor immunity and improving patient outcomes.
