Effect of TRAIL in combination with DDP on the expression of MDR1 gene in gastric cancer cells.

Introduction: Gastric cancer is one of the most common malignant tumor, and gastric cancer is the second most common cause of cancer mortality worldwide. Although chemotherapy is one of the most important treatment options for gastric cancer, and could improve the overall survival rate and quality of live, one significant reason for its failure is multidrug resistance (MDR).

Aim: To study the effect of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) combined with chemotherapeutic drug cisplatin (DDP) on the expression of multidrug resistance gene 1 (MDR1) in the gastric cancer cell line SGC-7901/VCR.

[Textual research on the distribution and circulation of Yi lei yuan rong (Fighting Diseases in Medical Field)].

Written by Wang Hao-gu (1200-1264) of the Yuan Dynasty, Yi lei yuan rong (Fighting Diseases in Medical Field) includes 12 volumes, with the twelve channels as its outline. It first describes the cold pathogenic diseases, and appended with the miscellaneous diseases. It is characterized by breaking the boundaries of cold pathogenic diseases and miscellaneous diseases, not only introducing the syndrome differentiation of six channels theory into the treatment of miscellaneous diseases, but also using the prescriptions of miscellaneous diseases for the treatment of six channels syndromes.