Publications by authors named "Qiao-Ming Deng"
Article Synopsis
- * Research involving immunohistochemistry and drug response tests showed a positive link between SIVA-1 levels and the effectiveness of DDP in treating GC, unlike with other drugs like 5-FU and adriamycin.
- * Overexpression of SIVA-1 alongside DDP treatment was found to enhance tumor suppression by increasing certain proteins (PCBP1) and reducing others (Bcl-2, Bcl-xL), suggesting SIVA-1 could be a marker
SIVA-1 has been shown to affect apoptotic processes in various different cell lines, and SIVA-1 significantly contributes to the decreased responsiveness of cancer cells to some chemotherapy agents. However, whether SIVA-1 has potential application in gastric cancer remains unknown. Therefore, the objective of this investigation was to clarify the distinct function of SIVA-1 in chemotherapeutic drug resistance within a living murine model with gastric malignancy, and initially elucidate the underlying mechanisms.
View Article and Find Full Text PDFBackground And Aims: Now that the debate about the safety and effectiveness of laparoscopic versus open surgery is over, attention has turned to innovations that can verify whether minimizing the impact of laparoscopy on the abdominal wall can further reduce pain, improve patient comfort, lead to superior cosmesis, and reduce morbidity. The aim of this study was to further explore the application value of totally laparoscopic right hemicolectomy with transcolonic natural orifice specimen extraction (NOSE) and to evaluate the short-term efficacy of transcolonic NOSE surgery for resecting specimens of ascending colon cancer.
Methods: From January 2016 to May 2017, a retrospective study was conducted in Guangxi.
Siva‑1 is a well‑known anti‑apoptosis protein that serves a role in multiple types of cancer cells. However, whether Siva‑1 affects multidrug resistance via the NF‑κB pathway in gastric cancer is currently unknown. The present study aimed to determine the possible involvement of Siva‑1 in gastric cancer anticancer drug resistance in vitro.
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