Publications by authors named "Qiao Zhenglei"

Article Synopsis
  • * Using metagenomic sequencing, researchers identified 19 types and 248 subclasses of ARGs across 53 rodent individuals, finding significant differences in several ARGs between species.
  • * The findings suggest that high levels of certain ARGs (macrolides, lincoamides, tetracyclines, β-lactams) could be linked to the rodents' habitats and diets, shedding light on the transmission risks of ARGs.
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Article Synopsis
  • Zokors, a type of subterranean rodent, evolved from lowlands to high elevations after the Qinghai-Tibet plateau uplifted around 3.6 million years ago, adapting to hypoxia and hypercapnia.
  • A genomic study of six zokor species revealed 18 significant chromosomal inversions in the high-elevation species Eospalax baileyi compared to its lower-elevation relatives.
  • Genetic variations linked to the upregulation of key genes involved in hypoxia response and enhanced lung size in E. baileyi highlight the genetic adaptations that help these rodents thrive in oxygen-poor environments.
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The phylogeny and speciation of subterranean zokors in China are unclear, as previous studies on morphology and limited molecular markers have generated conflicting results. This study unraveled the complex evolutionary history of eight zokor species in China based on de novo assembly at chromosome level and whole-genome sequencing of 23 populations. We found extensive phylogenetic discordances between nuclear and mitochondrial phylogenies, and different coalescent phylogenies, which could be explained by introgression and incomplete lineage sorting (ILS).

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SignificanceWhether sympatric speciation (SS) is rare or common is still debated. Two populations of the spiny mouse, , from Evolution Canyon I (EC I) in Israel have been depicted earlier as speciating sympatrically by molecular markers and transcriptome. Here, we investigated SS both genomically and methylomically, demonstrating that the opposite populations of spiny mice are sister taxa and split from the common ancestor around 20,000 years ago without an allopatric history.

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Oxygen plays a pivotal role in the metabolism and activities of mammals. However, oxygen is restricted in some environments-subterranean burrow systems or habitats at high altitude or deep in the ocean-and this could exert hypoxic stresses such as oxidative damage on organisms living in these environments. In order to cope with these stresses, organisms have evolved specific strategies to adapt to hypoxia, including changes in physiology, gene expression regulation, and genetic mutations.

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In order to reduce the stress response of animals in animal transportation, it is often used to feed the animals with sedative drugs combined with compound vitamin B. In this article, we will randomly divide 16 amur tiger into the control group and the experimental group. The drug intervention is carried out in the experimental group.

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Background: CD36 is a multifunctional membrane receptor and is expressed in several cell lines. Individuals who lack platelet (PLT) CD36 are at risk for immunization against this antigen, leading to several clinical syndromes. This study aimed to investigate the frequency and molecular basis of CD36 deficiency in Shanghai.

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