Publications by authors named "Qiao Yun Tong"
Article Synopsis
- Sinomenine (SN) has been clinically used for treating autoimmune diseases like lupus and rheumatoid arthritis, showing benefits such as anti-inflammation and suppression of immune responses.
- In a study, it was found that SN effectively inhibits macrophage activation induced by lipopolysaccharide (LPS) by down-regulating inflammatory cytokines and key proteins in the TLR4/NF-κB signaling pathway.
- The research suggests that SN's mechanism involves blocking the TLR4/NF-κB pathway, which could lead to new therapeutic strategies for managing inflammatory responses.
Hepatitis B virus (HBV) e antigen (HBeAg) is associated with viral persistence and pathogenesis. Resistance of HBV-infected hepatocytes to apoptosis is seen as one of the primary promotors for HBV chronicity and malignancy. Fas receptor/ligand (Fas/FasL) and the tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) system plays a key role in hepatic death during HBV infection.
View Article and Find Full Text PDFThe anti-inflammatory activities of fucoxanthin, a marine carotenoid derived from the macroalgae and microalgae, have been demonstrated in the previous studies. However, the effect of fucoxanthin on ulcerative colitis (UC), an inflammatory bowel disease, was still unclear. In this study, we evaluated the anti-inflammatory effect of fucoxanthin on dextran sulfate sodium(DSS)-induced colitis in mice.
View Article and Find Full Text PDFHepatitis B virus core protein (HBc) is expressed preferentially in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). HBc can function as an oncogene arising from its gene regulatory properties, but how it contributes functionally to hepatocarcinogenesis remains unclear. In this study, we determined the molecular and functional roles of HBc during HBV-associated hepatocellular tumorigenesis.
View Article and Find Full Text PDFObjective: This study aimed to investigate the protective effect of curcumin on chronic ethanol-induced liver injury in mice and to explore its underlying mechanisms.
Materials And Methods: Ethanol-exposed Balb/c mice were simultaneously treated with curcumin for 6 weeks. Liver injury was evaluated by biochemical and histopathological examination.