A Novel Dual Cross-linking Reagent for Dentin Bonding Interface Stability.

The cross-linking reagent has been proposed as a means of modifying dentin collagen, inhibiting matrix metalloproteinase activities, and enhancing bond durability during dentin bonding procedures. This study aimed to synthesize an operation-friendly dual cross-linking reagent-3-(4-formyphenoxy)-2-hydroxypropyl methacrylate (FPA)-to assess its ability to cross-link dentin collagen and reduce enzymatic activity at the bonding interface. Cytotoxicity was evaluated by a cell counting kit-8 test and calcein AM/propidium iodide assay.

Block Architectures in 2D Polymer Networks Fabricated via Sequential Copolymerization in a Metal-Organic Framework.

Two-dimensional (2D) polymer network monolayers with novel block architectures were fabricated via sequential copolymerization within a pillared-layer metal-organic framework (MOF) that served as the reaction template. The MOF provides a confined 2D nanospace, restricting the crosslinking copolymerization of vinyl monomers to two dimensions. Sequential crosslinking copolymerization of methyl methacrylate and styrene, regulated by the reversible addition-fragmentation chain transfer (RAFT) process, resulted in the formation of 2D block architectures with 'patchy' domains consisting of crosslinked poly(methyl methacrylate) and polystyrene segments.

Epigenomic Landscape of Human Cumulus Cells in Premature Ovarian Insufficiency Using Single-Base Resolution Methylome and Hydroxymethylome.

Premature ovarian insufficiency (POI) has recently been reported to be linked with epigenetic changes. Previous studies have focused on the regulation of individual genes associated with ovarian function through single-gene epigenetic variations; however, there is a deficiency in the comprehensive comprehension of the epigenetic profile for POI. Therefore, we conducted a multi-omics study integrating methylation, hydroxymethylation and transcriptome sequencing analyses in cumulus cells from women with POI and their matched controls.

Recent Progress in Block Copolymer Self-Assembly for the Fabrication of Structural Color Pigments.

The self-assembly of block copolymers (BCPs) into photonic materials has garnered increasing interest due to the versatility and ease of fabrication offered by the synthesized building blocks. BCPs are highly tunable, with their self-assembled structures' size being adjustable by modifying the block lengths, molecular weight(M), and polymer composition. This review provides a concise summary of the use of BCPs as photonic pigments, which generate color through structural manipulation rather than relying on chemical pigmentation.

Association between volatile organic compounds and circadian syndrome among pre- and postmenopausal women: A population-based study.

Air pollution is closely associated with the development of multiple metabolic diseases. Circadian syndrome (CircS), as an extended concept of metabolic syndrome (MetS), has been proven to be a better predictor of metabolic diseases than MetS. However, the relationship between volatile organic compounds (VOCs) and CircS in pre- and postmenopausal remains unclear.

Overexpression and alternative splicing of the glutamate-gated chloride channel are associated with emamectin benzoate resistance in the rice stem borer, Chilo suppressalis Walker (Lepidoptera: Crambidae).

Background: The rice stem borer, Chilo suppressalis Walker (Lepidoptera: Crambidae), is a damaging pest of rice worldwide. Following the evolution of C. suppressalis resistance to diamide and abamectin insecticides, emamectin benzoate (EB) became a key insecticide for the control of this species in China.

Corrigendum: Advances in retinal imaging biomarkers for the diagnosis of cerebrovascular disease.

[This corrects the article DOI: 10.3389/fneur.2024.

Highly Sensitive T-Shaped Quartz Tuning Fork Based CH-Light-Induced Thermoelastic Spectroscopy Sensor with Hydrogen and Helium Enhanced Technique.

In this paper, a highly sensitive methane (CH) sensor based on light-induced thermoelastic spectroscopy (LITES) and a T-shaped quartz tuning fork (QTF) with hydrogen (H) and helium (He) enhancement techniques are reported for the first time. The low resonant frequency self-designed T-shaped QTF was exploited for improving the energy accumulation time. H and He were utilized as surrounding gases for the T-shaped QTF to minimize energy loss, thereby enhancing the sensitivity of the LITES sensor.

Valley splitting of monolayer HfCO by the spin-orbit coupling effect: first principles calculations using the HSE06 methods.

Electrons have not only charge and spin degrees of freedom, but also additional valley degrees of freedom. The search for valleytronic materials with large valley splits is important for the development of valleytronics. In this work, we applied first principles computations to calculate 1 L HfCO at the level of HSE06.

Therapeutic potential of flavonoids from traditional Chinese medicine in pancreatic cancer treatment.

Pancreatic cancer (PC) is a highly aggressive malignancy with rising mortality rates globally. Its diagnosis is often challenging due to its asymptomatic nature in the early stages. Consequently, most patients receive a poor prognosis, with low survival rates within 5 years, as the disease is typically detected at an advanced stage, complicating effective treatment.

Large Band Splitting in g-Wave Altermagnet CrSb.

Altermagnetism (AM), a newly discovered magnetic state, ingeniously integrates the properties of ferromagnetism and antiferromagnetism, representing a significant breakthrough in the field of magnetic materials. Despite experimental verification of some typical AM materials, such as MnTe and MnTe_{2}, the pursuit of AM materials that feature larger spin splitting and higher transition temperature is still essential. Here, our research focuses on CrSb, which possesses Néel temperature of up to 700 K and giant spin splitting near the Fermi level (E_{F}).

[ alleviates dextran sulfate sodium salt-induced ulcerative colitis in mice: a preliminary study].

Objective: To investigate the alleviation of infection on dextran sulfate sodium salt (DSS)-induced ulcerative colitis in mice, and to explore the underlying mechanism.

Methods: Thirty male C57BL/6J mice of the SPF grade, each weighing approximately 25 g, were randomly divided into three groups, including the blank control group (NC group), DSS modeling group (DSS group), and treatment group (Nb + DSS group), of 10 mice in each group. Mice in the DSS group were orally administered with 3.

Deferoxamine Treatment Effectively Prevents Periodontitis Progression by Reducing Inflammation and Osteoclastogenesis in Experimental Periodontitis Rats.

Purpose: Although the anti-inflammatory properties of the hypoxia-mimetic drug deferoxamine (DFO) have been reported, its potential as a treatment for periodontitis remains unknown. This study investigated the therapeutic benefits of DFO on osteoclastogenesis and inflammation in periodontitis progression.

Methods: RAW264.

FNIRS-Based Energy Landscape Analysis to Signify Brain Activity Dynamics of Individuals With Depression.

Background: Major depressive disorder (MDD) is one of the most common mental disorders, and the number of individuals with MDD (MDDs) continues to increase. Therefore, there is an urgent need for an objective characterization and real-time detection method for depression. Functional near-infrared spectroscopy (fNIRS) is a non-invasive tool, which is widely used in depression research.

Fermentation with Bacillus natto and Bifidobacterium improves the functional, physicochemical properties, and taste qualities of coix seed-natto.

Coix seed-natto (CS-natto) is a nutritious food rich in various functional components such as nattokinase (NK), and the strains' fermentation is crucial for enhancing its quality. This work utilized Bacillus natto GUTU09 (B9) and Bifidobacterium animalis subsp. lactis BLH1 or BLH6 to ferment soybeans that were soaked in a saccharified liquid made from CS, resulting in the preparation of CS-natto, studied the physicochemical and functional characteristics during fermentation, and analyzed the correlation of various indicators.

Corrosion-resistant NiFe anode towards kilowatt-scale alkaline seawater electrolysis.

Development of large-scale alkaline seawater electrolysis requires robust and corrosion-resistant anodes. Here we propose engineering NiFe layered double hydroxide (LDH)-based anodes by incorporating a series of anions into the LDH interlayers. The most optimal NiFe LDH anode with intercalated phosphates demonstrates stable operation at a high current density of 1.

Protective Role of Indole-3-Acetic Acid Against Typhimurium: Inflammation Moderation and Intestinal Microbiota Restoration.

Indole-3-acetic acid (IAA), a metabolite derived from microbial tryptophan metabolism, plays a crucial role in regulating intestinal homeostasis. However, the influence and potential applications of IAA in the context of animal pathogen infections remain underexplored. This study investigates the prophylactic effects of IAA pretreatment against typhimurium (ST) SL1344 infection, focusing on its ability to attenuate inflammatory responses, enhance intestinal barrier integrity, inhibit bacterial colonization, and restore colonic microbiota dysbiosis.

RuMnO Electrocatalyst for Durable Oxygen Evolution in Acid Seawater.

Currently, direct electrolysis of seawater for green hydrogen production is primarily focused on neutral and alkaline systems. However, the precipitation of calcium and magnesium ions restricts the advancement of this technology. An acidic system can effectively address this issue.

Division mechanism of labor in Diqing Tibetan Pigs gut microbiota for dietary fiber efficiently utilization.

The Diqing Tibetan (TP) pig is an roughage tolerance breed that inhabits an area with the highest altitude distribution in the world and can be maintained on a diet containing 90 % forage material in confined production systems. Our results showed that TP pigs had a strong capability for high-efficiency utilization of arabinose and xylose. Metagenomic analysis revealed that the secretion of carbohydrate esterases was mainly undertaken by fecal strains of Microbacterium, Alistipes, Acinetobacter, and Faecalibacterium, while Microbacterium, Prevotella, Turicibacter, Lactobacillus, Clostridium, and Streptococcus were responsible for most of the secretion of glycoside hydrolases.

Dynamic Creation of a Local Acid-like Environment for Hydrogen Evolution Reaction in Natural Seawater.

Electrolysis of natural seawater driven by renewable energy is practically attractive for green hydrogen production. However, because precipitation initiated by an increase in local pH near to the cathode deactivates catalysts or blocks electrolyzer channels, limited catalysts are capable of operating with untreated, natural seawater (., pH 8.

Dyadic interventions for cancer patient-caregiver dyads: A systematic review and network meta-analysis.

Background: Cancer imposes significant psychological distress on both patients and caregivers. Dyadic interventions are designed to concurrently address the health problems of both, yet there remains limited evidence as to which specific dyadic interventions yield the most effective outcomes for both partners.

Objectives: To systematically synthesize and evaluate the comparative efficacy of various dyadic interventions on a wide range of outcomes within cancer patient-caregiver dyads.

Oxygen Evolution Enhancement of Oxalate-Based Nickel-Iron MOF through Bipyridine Coordinated Strategy.

The catalytic performance of oxalate-based Ni-Fe metal-organic frameworks (MOFs) in the oxygen evolution reaction (OER) was investigated via a coordination strategy. The bidentate chelating ligand 2,2'-bpy (2,2'-bipyridine), was utilized to improve the catalytic kinetics under ambient conditions. The results revealed that a MOF-to-MOF transformation including the formation of [M(2,2'-bpy)] (M = Ni/Fe, = 1-3) could boost alkaline OER, giving an impressive ultralow overpotential of 220 mV at a current density of 10 mA/cm in a 1 M KOH solution, surpassing the performance of control group activity of oxalate-based Ni-Fe MOF.