Publications by authors named "Qiao Li Yang"

Agricultural by-products of sesame are promising bioresources in food processing. This study extracted lignin from the by-products of sesame oil production, namely, the capsules and straw of black and white sesame. Using acid, alkali, and ethanol methods, 12 distinct lignins were obtained to prepare biochar, aiming to investigate both the structural characteristics of lignin-based biochar (LBB) and its ability to remove benzo[a]pyrene (BaP) from sesame oil.

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In this study, three activators and two activation methods were employed to activate sesame lignin-based biochar. The biochar samples were comprehensively characterized, their abilities to adsorb benzo[a]pyrene (BaP) from sesame oil were assessed, and the mechanism was analyzed. The results showed that the biochar obtained by one-step activation was more effective in removing BaP from sesame oil than the biochar produced by two-step activation.

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Background: Neurodegenerative retinal diseases such as retinitis pigmentosa are serious disorders that may cause irreversible visual impairment. Ferroptosis is a novel type of programmed cell death, and the involvement of ferroptosis in retinal degeneration is still unclear. This study aimed to investigate the related ferroptosis genes in a mice model of retinal degeneration induced by light damage.

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Article Synopsis
  • The study focuses on the loss of retinal photoreceptors associated with ciliopathy disorders and explores the effects of a homozygous Cep250 knockout mouse model.
  • Researchers utilized various methods, including untargeted metabolomics and imaging techniques, to investigate retinal degeneration and found significant changes in the outer nuclear layer and scotopic responses.
  • Results indicated a mislocalization of proteins linked to arginine metabolism in Cep250-/- mice, suggesting that disrupted arginine pathways play a crucial role in retinal degeneration in these conditions.
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A unique ring C-expanded angucyclinone, oxemycin A (), and seven new ring-cleavage derivatives (- and -) were isolated from the marine actinomycete KCB-132, together with eight known analogues (- and -). Their structures were elucidated by spectroscopic analyses, single-crystal X-ray diffractions, and NMR and ECD calculations. Among these atypical angucyclinones, compound represented the first seven-membered ketoester in the angucyclinone family, which sheds light on the origin of fragmented angucyclinones with C-ring cleavage at C-12/C-12a in the Baeyer-Villiger hypothesis, such as -, while the related "nonoxidized" analogues - seem to originate from a diverse pathway within the Grob fragmentation hypothesis.

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Objective: Written words demonstrated specific effects on biochemical measures and cell growth in cultured mammalian cells in previous study. We examined the protection and reparative effects of Chinese texts with positive meaning and the word "Buddha" on oxidative-damaged cells, with the goal of exploring the therapeutic effect of such characters.

Methods: The human embryonic kidney cell line HEK293T was utilized, with the oxidative- damaged cell model produced by hydrogen peroxide (HO).

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Article Synopsis
  • The study investigated the role of miR-96, a member of the retinal microRNA-183 cluster, in the development and function of photoreceptors in mice using CRISPR/Cas9 technology to create a mutant model.
  • Findings showed that miR-96 mutant mice experienced a delay in cone development, with mislocalization of cone-specific markers and alterations in retinal structure and function observable through ERG and OCT tests.
  • Despite the initial developmental delays, the study concluded that the absence of miR-96 does not completely halt photoreceptor development, indicating its critical role in the maturation of cones in the retina.
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Strepyrazinone (, a tricyclic diketopiperazine derivative with a carbon skeleton unprecedented in natural products, was isolated from the marine-derived sp. B223. Its structure was elucidated by spectroscopic analyses and electronic circular dichroism calculation.

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(±)-Pratenone A (1), the first representative of natural 3-(1-naphthyl)-2-benzofuran-1(3H)-one polyketides, was isolated from a marine-derived Streptomyces pratensis strain KCB-132 together with three other new analogues (2-4). Its structure was assigned by spectroscopic analysis, and the absolute configurations of the two enantiomers separated by high-performance liquid chromatography were determined by single-crystal X-ray diffraction and electronic circular dichroism calculations. The solvent-induced racemization of 1 and a proposed biogenetic pathway to 1-4 from the co-isolated angucyclinone precursor, as well as their biological activity, are also discussed.

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LncRNA play important roles in regulation of host immune and inflammation responses in defending bacterial infection. Clostridium perfringens (C. perfringens) type C is one of primary bacteria leading to piglet diarrhea and other intestinal inflammatory diseases.

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The complete mitochondrial genome sequence of the Qinghai Tibetan pig was first determined in this study. The total length of the mitogenome is 16,720 bp. Indicating the an A + T(60.

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With the development and change of Uygur medicine, The sources,medicinal parts and producing area of some Uygur Medicine have changed. It is more important to master the classification, distribution and change of Uygur medicinal materials. These were more than 1 200 kinds Uygur medicine in history were resaerched by field investigation, philological research, and textual research, which main source of original plant were 140 families, 510 genera, 840 species; and source of original animal were 76 families, 107 genera, the original animal 141 species; 55 kinds of original mineral, which main producer were Xinjiang and Central Asia, West Asia, the Mediterranean, and North Africa, Southeast Asia and other provinces in China, there are individual medicinal materials from the Americas, Europe and other places.

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Maxim, belonging to the Violaceae plant family, is traditionally used in Uighur medicine for treating pneumonia, headache, and fever. There is, however, a lack of basic understanding of its pharmacological activities. This study was designed to observe the effects of the ethanol extract (TSM) from Maxim on the inflammation response in acute lung injury (ALI) induced by LPS and the possible underlying mechanisms.

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Objective: To investigate the effects of different processing methods on analgesic effect and toxicity of Strychni Semen, and to provide the scientific basis of milk-impregnated-processing-technology of traditional Uighur medicine for toxic medicines.

Methods: Three different methods, frying with sand of traditional Chinese medicine (1), cooled milk-impregnated-processing-technology of traditional Uighur medicine (2), and heated milk-impregnated-processing-technology of traditional Uighur medicine (3) were used to process raw Strychni Semen and the processed products were compared with those in the raw drug (4). Karber method was used to caculate the LD50.

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Objective: To study the chemical constituents of Sophora alopecuroides seeds.

Methods: Five compounds were isolated and purified from this plant by various chromatographic methods. Structures were elucidated on the basis of spectral analysis.

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