Publications by authors named "Qianzhi Shi"
Background: Ischaemic stroke can lead to many complications, but treatment options are limited. Icariin is a traditional Chinese medicine with reported neuroprotective effects against ischaemic cerebral injury; however, the underlying mechanisms by which icariin ameliorates cell apoptosis require further study.
Purpose: This study aimed to investigate the therapeutic potential of icariin after ischaemic stroke and the underlying molecular mechanisms.
Article Synopsis
- Sepsis-induced cardiac injury is a major cause of death, with reactive oxygen species (ROS)-mediated ferroptosis and inflammation playing key roles in this process.
- The study designed a new treatment (CeCH) using ceria nanozyme and curcumin to target both ferroptosis and inflammation in heart cells.
- Results showed that CeCH effectively reduced ROS, promoted healthy macrophage behavior, and helped recover cardiac function in sepsis models, indicating its potential for clinical application.