Publications by authors named "Qianshan Ke"

Article Synopsis
  • The study investigated the patterns of Chinese medicine (CM) syndromes among chronic hepatitis B virus (HBV) carriers in the immunotolerant phase (ITP) at a hospital in China, analyzing various symptoms and biochemistry.
  • Out of 185 patients, most exhibited CM syndromes, classified into 15 types, with the top three being Spleen-Kidney deficiency, Liver qi depression, and others, indicating a prevalence of deficiency syndromes over excess syndromes.
  • The findings suggest that addressing these syndromes, particularly by enhancing Spleen-Kidney function and alleviating Liver qi stagnation, may improve the condition of chronic HBV carriers in ITP.
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Objective: To explore the relationship between the syndrome types in traditional Chinese medicine (TCM) and serum HBV DNA load in chronic HBV carriers positive for HBeAg.

Methods: According to the TCM syndrome types, 185 chronic HBV carriers with HBeAg positivity were classified into single syndrome group (liver Qi depression, kidney Qi deficiency, spleen Qi deficiency, and kidney Yang deficiency), compound syndrome group, and unidentifiable syndrome group; based on the nature of the condition in TCM terms, the patients were classified into excess syndrome group, deficiency syndrome group and comorbidity syndrome group. The serum HBV DNA levels in these cases were analyzed in relation to the TCM syndrome types and disease nature.

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Aim: To observe the therapeutic effects of new traditional Chinese medicine (TCM) therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients.

Methods: Using stratified random sampling according to fibrinogen (Fib) levels, 145 liver cirrhosis patients due to hepatitis B complicated by coagulation disorder were treated. Of them, 70 in research group were treated with TCM by "nourishing yin, cooling blood and invigorating blood circulation" and Western medicine, 75 in control group were treated with conventional Western medicine.

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Objective: To investigate the effects of glycyrrhizin (GL) on the expression of hepatitis B virus e antigen (HBeAg), HBV DNA, Toll-like receptors 2,4 (TLR2,4) and proliferation of cells in HepG2.2.15 cell line.

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