Sensory Processing Sensitivity and Quality of Life Among Cancer Patients and Their Family Caregivers: An Actor-Partner Interdependence Model Analysis.

Objective: Studies report a negative impact of sensory processing sensitivity (SPS) on health outcomes, but evidence from patient-caregiver dyads is scarce. This study aimed to simultaneously examine the independent and interdependent impact of SPS on quality of life (QoL) among cancer patients and their family caregivers.

Methods: In this two-stage random sampling cross-sectional study, we conducted a dyadic analysis of data collected from cancer patients and their family caregivers in southwest China.

Enhanced detection of Mycobacterium Tuberculosis using nanogold-based silver staining enhancement.

Background: Tuberculosis (TB) is a global health challenge from a single infectious agent, Mycobacterium tuberculosis (MTB), and it demands improved diagnostics and therapies.

Objective: This work explored a novel method for detecting MTB by combining nanogold labeling (NGL) technology with silver staining to enhance sensitivity and specificity.

Methods: Nanogold particles (NGPs) were characterized using ultraviolet absorption spectroscopy (UVAS), and their morphology was observed via transmission electron microscopy (TEM).

Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium.

Introduction: Previous studies have shown disrupted effective connectivity in the large-scale brain networks of individuals with major depressive disorder (MDD). However, it is unclear whether these changes differ between first-episode drug-naive MDD (FEDN-MDD) and recurrent MDD (R-MDD).

Methods: This study utilized resting-state fMRI data from 17 sites in the Chinese REST-meta-MDD project, consisting of 839 patients with MDD and 788 normal controls (NCs).