Publications by authors named "Qianqian Zhu"

Background: Owing to the particularities of their physical characteristics, older patients undergoing surgery under general anesthesia experience great surgical traumas. Thus, exploring more refined and individualized nursing approaches is an urgent need to mitigate the negative effects of surgery on such patients.

Aim: To analyze the influence of preoperative comprehensive education on anxiety, depression, pain, and sleep in older patients who underwent surgery under general anesthesia.

View Article and Find Full Text PDF

Purpose: The purpose of this article is to report a case of acute superior mesenteric artery embolism due to infective endocarditis treated with endovascular therapy.

Case Report: A patient with infective endocarditis was admitted to the hospital with abdominal pain, and abdominal enhanced computer tomography showed acute superior mesenteric artery embolism. He underwent urgent percutaneous mechanical thrombectomy and stenting to open the superior mesenteric artery and restore blood supply to the intestine.

View Article and Find Full Text PDF

The effects of the Maillard reactions of peanut Ara h 2.01 with respective glucose and xylose on its conformation and allergenicity were investigated. Circular dichroism (CD) spectral studies showed that short-term heating alone with reducing sugars did not change protein secondary structures, but after undergoing Maillard reactions, its secondary structures changed with some α-helices being transformed into β-sheets and random coils.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated how using letrozole with an antagonist protocol during IVF affected live birth rates and safety for mothers and babies.
  • It included women treated from 2007 to 2021 and showed that letrozole co-treatment had similar live birth rates compared to antagonist protocol alone, with better outcomes for women with higher body mass index and ovarian response.
  • Additionally, letrozole use was linked to lower rates of gestational diabetes and small-for-gestational-age babies.
View Article and Find Full Text PDF

Creating new functional materials that efficiently support noble metal catalysts is important and in high demand. Herein, we develop a self-polycondensation flux synthesis strategy that can produce olefin-linked covalent organic framework (COF) platforms with high crystallinity and porosity as the supports of Pd nanoparticles for electrocatalytic nitrogen reduction reaction (ENRR). A series of "two in one" monomers integrating aldehyde and methyl reactive groups are rationally designed to afford COFs with square-shaped pores and ultrahigh chemical stability (e.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers developed new materials called mesoporous covalent organic frameworks (COFs) to improve enzyme stability and activity through a rapid chemical process.
  • The COFs are designed to easily bind enzymes thanks to their hydroxyl groups and can significantly enhance enzyme performance, particularly lipase, when exposed to solar light.
  • This innovative method not only improves the efficiency of biocatalysts but is also environmentally friendly, making it suitable for large-scale application.
View Article and Find Full Text PDF
Article Synopsis
  • The monolayer MoSiN shows great environmental stability, moderate band gap, and excellent mechanical properties, but its low carrier mobility restricts its use in field-effect transistors (FETs).
  • This study investigates a new family of β-phase MXN monolayers, revealing they possess strong stability and varying band gaps, with MoSiN, MoGeN, WSiN, and WGeN identified as potential semiconductors.
  • WGeN stands out with impressive anisotropic charge transport and high carrier mobility, making these new materials promising for expanding the 2D MXZ material family and improving FET applications.
View Article and Find Full Text PDF
Article Synopsis
  • Frailty is linked to increased health risks in older adults, but diagnosing it is complicated due to varied symptoms and underlying causes, prompting a study to explore mitochondrial function as a potential biomarker for frailty.* -
  • In a study of 393 participants aged 25-100, researchers assessed frailty using the physical frailty phenotype scale and analyzed various mitochondrial functions and morphology in peripheral blood mononuclear cells (PBMCs).* -
  • Results showed significant differences in mitochondrial characteristics and functions between frail and non-frail older adults, highlighting potential correlations between mitochondrial health and frailty status, particularly regarding factors like mtDNA copy number and respiratory function.*
View Article and Find Full Text PDF
Article Synopsis
  • * Sugammadex can reverse the effects of rocuronium-induced neuromuscular blockade but may also provoke anaphylaxis, indicating a need for better treatment options.
  • * Research into the antibodies of patients with rocuronium sensitivity found a diverse range that can activate anaphylaxis; high-affinity antibodies capable of reversing rocuronium effects were isolated, suggesting new avenues for diagnosis and treatment.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the relationship between ambient air pollution, specifically PM particulate matter, and birth weight outcomes among twins conceived through in vitro fertilization in Shanghai from 2007 to 2021.
  • Results show that higher levels of PM exposure during pregnancy are linked to increased birth weights and a higher risk of large for gestational age (LGA) among twins, with more significant effects observed in larger fetuses compared to smaller ones.
  • The research concludes that exposure to PM and its components, including sulfate, contributes to fetal overgrowth in twin pregnancies.
View Article and Find Full Text PDF

Background: Low serum ceruloplasmin concentration is considered robust marker for Wilson disease (WD) screening, measuring serum ceruloplasmin oxidase activity might be an even more valuable diagnostic tool, but it has not been sufficiently studied.

Methods: All patients who were assessed for serum ceruloplasmin oxidase activity between January 1, 2016, and September 2, 2019, were enrolled in this study. The diagnostic performance of serum ceruloplasmin oxidase activity was analyzed using receiver operating characteristic curve analysis (ROC), Spearman's rank correlation, and Mann-Whitney U test.

View Article and Find Full Text PDF

Bone toxicities are common among paediatric patients treated for acute lymphoblastic leukaemia (ALL) with potentially major negative impact on patients' quality of life. To identify the underlying genetic contributors, we conducted a genome-wide association study (GWAS) and a transcriptome-wide association study (TWAS) in 260 patients of European-descent from the DFCI 05-001 ALL trial, with validation in 101 patients of European-descent from the DFCI 11-001 ALL trial. We identified a significant association between rs844882 on chromosome 20 and bone toxicities in the DFCI 05-001 trial (p = 1.

View Article and Find Full Text PDF

Background: Chronic stress induces cognitive deficits. There is a well-established connection between the enteric and central nervous systems through the microbiota-gut-brain (MGB) axis. However, the effects of the gut microbiota on cognitive deficits remain unclear.

View Article and Find Full Text PDF

Objectives: The transversus abdominis plane (TAP) block has proven efficacy and is an important component of multimodal analgesia in laparoscopic cholecystectomy (LC). The external oblique intercostal (EOI) block can provide a dermatomal sensory blockade of T6 to T10 using an anterior axillary line injection. The bilateral rectus sheath (RS) block can significantly reduce early postoperative pain caused by umbilical or periumbilical incisions.

View Article and Find Full Text PDF
Article Synopsis
  • * The self-assembly of coconut protein led to changes like decreased fluorescence and increased surface hydrophobicity, and was enhanced by adding fucoidan, which helped improve solution stability.
  • * Results showed that the aggregation state influenced the protein’s ability to reduce surface tension, with emulsions made from self-assembled proteins demonstrating better droplet size, stability, and rheological properties, suggesting potential uses in the food industry.
View Article and Find Full Text PDF

Objective: Our objective was to investigate the efficacy of letrozole co-treatment in an antagonist protocol for infertile women with polycystic ovary syndrome (PCOS).

Patients And Methods: This retrospective cohort study included infertile women with PCOS undergoing IVF/ICSI with and without letrozole co-treatment in an antagonist protocol from 2007-2021 at Shanghai Ninth People's Hospital (Shanghai, China). A total of 1559 participants were enrolled, with 1227 women in the antagonist group and 332 women in the letrozole co-treatment group.

View Article and Find Full Text PDF

As a widely used pesticide, abamectin could be a threat to nontarget organisms. In this study, the toxic mechanism of abamectin on osmoregulation in Procambarus clarkii was explored for the first time. The results of this study showed that with increasing abamectin concentration, the membrane structures of gill filaments were damaged, with changes in ATPase activities, transporter contents, biogenic amine contents, and gene expression levels.

View Article and Find Full Text PDF
Article Synopsis
  • Metabolic and alcohol-associated liver disease (MetALD) has no effective treatment, but the water extract of Chrysanthemum morifolium Ramat. (WECM) shows promise due to its anti-inflammatory and hepatoprotective properties.
  • The study tested WECM on MetALD rats, assessing its impact on liver health and underlying mechanisms over a six-week period through various biochemical and microbiota analyses.
  • Results indicated that WECM significantly improved liver conditions, helped restore gut microbiota balance, activated beneficial signaling pathways, and enhanced lipid metabolism, suggesting its potential as a therapeutic agent for MetALD.
View Article and Find Full Text PDF
Article Synopsis
  • Hydrolyzed royal jelly peptide (RJP) shows potential as a skincare ingredient due to its promising health benefits, specifically in reducing oxidative damage and inflammation in skin cells.* -
  • The study found that RJP significantly enhances antioxidant levels and counteracts inflammation by modulating key inflammatory markers in human dermal fibroblasts (HDFs).* -
  • RJP demonstrated superior protective effects compared to unhydrolyzed royal jelly protein, suggesting its potential in managing skin disorders related to oxidative stress and inflammation.*
View Article and Find Full Text PDF
Article Synopsis
  • Nanoplastics pollution poses a significant global threat due to its potential toxicity, particularly affecting juvenile P. clarkii, a type of crayfish.
  • The study found that different concentrations of nanoplastics have distinct effects on growth and health, with lower concentrations stimulating antioxidant and immune responses, while higher concentrations cause harmful oxidative stress and damage.
  • These results highlight the need for further research into the impact of nanoplastics on crustaceans and their toxicological mechanisms, as they reveal both beneficial and detrimental effects based on concentration levels.
View Article and Find Full Text PDF

Background: Aortic aneurysm, characterized by abnormal dilation of the aorta, poses significant health risks. This study aims to investigate the interaction between 5-aminolevulinate synthase 2 () and GATA-binding protein 1 () in ferroptosis and oxidative stress responses in aortic aneurysm.

Methods: A weighted gene co-expression network analysis (WGCNA) was performed on the differentially expressed genes (DEGs) within the GSE9106 dataset to identify the key module.

View Article and Find Full Text PDF
Article Synopsis
  • - The catalytic oxidation of alcohols is vital in the chemical industry, and N-doped carbon materials with a large surface area are promising as metal-free catalysts for this reaction.
  • - In this study, researchers synthesized N-doped porous carbon using a specific polymer and NaCl, optimizing the ratio of polymer to NaCl and investigating how different pyrolysis temperatures affect the materials.
  • - The optimal N-doped carbon (CNN-1-9-900) exhibited a high surface area and nitrogen content, resulting in superior performance for oxidizing benzyl alcohol and its derivatives under moderate conditions.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the rising issue of subhealth among nursing staff in Shaanxi Province, defined as a state between health and illness, characterized by reduced vitality and adaptability.
  • It aims to assess subhealth levels, identify causes and risk factors, and propose strategies to improve the overall well-being of nurses.
  • Findings reveal that factors like physical activity, diet, occupational stress, and working conditions significantly influence nursing staff's subhealth, highlighting the need for targeted interventions.
View Article and Find Full Text PDF