Publications by authors named "Qianni Yang"

Alcoholic liver disease (ALD) is regarded as one of the main global health problems. Accumulated evidence indicates that fruit-derived polyphenols can lower the risk of ALD, this attributed to their strong antioxidant capacities. Thinned immature kiwifruits (TIK) are the major agro-byproducts in the production of kiwifruits, which have abundantly valuable polyphenols.

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Article Synopsis
  • Discarded unripe kiwifruits (DUKs) are a major byproduct in kiwifruit production, yet their potential as valuable food sources is underexplored due to limited knowledge on their phytochemicals compared to mature fruits.* -
  • A study comparing the phenolic compounds and bioactivity of unripe, mature, and overripe kiwifruits revealed that DUKs contain significantly higher levels of beneficial phenolic compounds and exhibit stronger antioxidant and anti-inflammatory properties.* -
  • The findings suggest that DUKs have considerable potential for use in the food industry, encouraging further exploration and development of their applications as functional foods.*
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Thinned unripe kiwifruits (TUK) are considered the major agro by-products in kiwifruit production. To promote their potential applications, polyphenols and biological effects of unripe fruits from nine commercial kiwifruit cultivars were compared. Our findings showed that TUK were rich in bioactive polyphenols, which varied greatly by different cultivars.

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Colorectal cancer (CRC) is one of the most common non-cutaneous malignancies, causing significant mortality and a substantial burden. This study aims to explore the role of KIAA1429 (also known as vir-like m6A methyltransferase associated [VIRMA]) protein in the radioresistance of CRC. CRC cells and a radioresistant cell line were cultured, and KIAA1429 expression was detected.

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High-mobility group box 1 (HMGB1) is a highly conserved nonhistone nuclear protein found in the calf thymus and participates in a variety of intracellular processes such as DNA transcription, replication and repair. In the cytoplasm, HMGB1 promotes mitochondrial autophagy and is involved in in cellular stress response. Once released into the extracellular, HMGB1 becomes an inflammatory factor that triggers inflammatory responses and a variety of immune responses.

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