CD86 +1057G/A polymorphism and susceptibility to Ewing's sarcoma: a case-control study.

The development of Ewing's sarcoma (ES) is a complex process resulting from interplay between mutations in oncogenes and tumor suppressors, host susceptibility factors, and cellular context. CD86 (B7-2) may affect cancer susceptibility by modulating T cell response. CD86 +1057G/A polymorphism (rs1129055) has been reported to be associated with various diseases.

[Comparison of long bone repair in tibia by vascularized fibular grafting of different sides].

Objective: To evaluate the clinical effect of repair of massive bone defect in tibia by vascularized fibula grafting of either sides.

Methods: Twenty-four cases of massive bone defect in tibia, among which 14 case were repaired by vascularized fibula grafting of the other side and another 10 cases were repaired by those of the same side, from 1987 to 1997 were followed up for 3 to 13 years; the functions of the operated limbs were evaluated according to Enneking Score System, and the outcome of the fibula grafts were assessed by radiographic examination with reference to the standard established by International Symposium on Limb Salvage.

Results: The average recover rate of the operated limbs in those repaired by the other side grafting was 80.