Publications by authors named "Qianhui Zheng"
The integration of drug molecular representations into predictive models for Drug Response Prediction (DRP) is a standard procedure in pharmaceutical research and development. However, the comparative effectiveness of combining these representations with genetic profiles for DRP remains unclear. This study conducts a comprehensive evaluation of the efficacy of various drug molecular representations employing cutting-edge machine learning models under various experimental settings.
View Article and Find Full Text PDFBackground: In response to SARS-CoV-2 mutations and waning antibody levels after two-dose inactivated vaccines, we assessed whether a third dose of recombinant protein subunit vaccine (ZF2001) boosts immune responses.
Methods: An open-label single-center non-random trial was conducted on people aged 18 years and above at five sites in China. All participants received a two-dose inactivated vaccine (CoronaVac) as their prime doses within 3-9 months of the trial.
Article Synopsis
- A study in Zhejiang Province, China, explored the effects of co-administering an inactivated COVID-19 vaccine (CoronaVac) with an influenza vaccine in healthy adults aged 18-59.
- The results showed that the immune response (measured by seroconversion rates) for those who received both vaccines together was not significantly worse than for those who received them separately, although those in the co-administration group had slightly lower antibody levels.
- Most side effects were mild and similar across all groups, indicating that co-administration of these vaccines is a feasible option.