Publications by authors named "Qianhua Gao"
Background: To investigate the inhibition mechanism of copper ions on Streptococcus mutans-Veillonella parvula dual biofilm.
Methods: S. mutans-V.
Article Synopsis
- This study investigates how compressive stress affects the growth and development of human dental pulp cells (hDPCs) during functional activities.
- Using a specialized four-point bending system, researchers applied low-density cyclic compressive stress to hDPCs for various time periods to assess changes in cell behavior.
- Results indicated that while compressive stress altered cell shape and promoted cell division, the expression of specific differentiation-related genes varied over time, highlighting the cells' sensitivity to mechanical forces.
Introduction: Piezo1 and Piezo2 are mechanosensitive membrane ion channels. We hypothesized that Piezo proteins may play a role in transducing ultrasound-associated mechanical signals and activate downstream mitogen-activated protein kinase (MAPK) signaling processes in dental cells. In this study, the expression and role of Piezo channels were investigated in dental pulp stem cells (DPSCs) and periodontal ligament stem cells (PDLSCs) after treatment with low-intensity pulsed ultrasound (LIPUS).
View Article and Find Full Text PDFIntroduction: Mesenchymal stem cells (MSCs) from dental tissues may respond to low-intensity pulsed ultrasound (LIPUS) treatment, potentially providing a therapeutic approach to promoting dental tissue regeneration. This work aimed to compare LIPUS effects on the proliferation and MAPK signaling in MSCs from rodent dental pulp stem cells (DPSCs) compared with MSCs from periodontal ligament stem cells (PDLSCs) and bone marrow stem cells (BMSCs).
Methods: Isolated MSCs were treated with 1-MHz LIPUS at an intensity of 250 or 750 mW/cm2 for 5 or 20 minutes.