Amide Iridium Complexes As Catalysts for Transfer Hydrogenation Reduction of -sulfonylimine.

Sulfonamide moieties widely exist in natural products, biologically active substance, and pharmaceuticals. Here, an efficient water-soluble amide iridium complexes-catalyzed transfer hydrogenation reduction of -sulfonylimine is developed, which can be carried out under environmentally friendly conditions, affording a series of sulfonamide compounds in excellent yields (96-98%). In comparison with organic solvents, water is shown to be critical for a high catalytic transfer hydrogenation reduction in which the catalyst loading can be as low as 0.

Two new phenolic glucosides from marine-derived fungus sp.

Two new phenolic glucosides, including a new -glycoside () and a new -glycoside (), were isolated from a marine-derived fungus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of was identified as -D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization.