Association of Genes , and with Milk Performance, Reproductive Traits and Heat Stress Response in Dairy Cattle.

In our previous study, we found that changes in plasma prolactin (PRL) concentration were significantly associated with heat stress in dairy cows, and that PRL plays an important role in milk performance. Microarray sequencing revealed that thyrotropin releasing hormone () and prolactin receptor (), two genes important for expression or function, may affect milk performance, reproduction, and heat stress response in dairy cattle. In this study, we further validated the genetic effects of the three genes in Chinese Holsteins.

Correction: Deng et al. Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Infection of Host Cells. 2023, , 235.

In the original publication [...

Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Infection of Host Cells.

The macrophage CD163 surface glycoprotein is a member of the SRCR family class B, which has been identified as the key trigger in host-pathogen interactions, but its specific roles in sensing () infection are largely unknown. Here, we investigated porcine CD163 in mediating the adhesion and immune response of using in vitro host-bacteria interaction models. CD163-overexpressing Chinese hamster ovary K1 cells (CHO-K1) showed obvious subcellular localization in the cytoplasm, especially in the cytomembrane.