The study aimed to explore how human dental pulp cells (hDPCs) grow and differentiate when placed on various bioactive scaffolds.
Researchers extracted hDPCs from impacted wisdom teeth of young adults, verified their identity, and tested their proliferation on three different scaffold types: collagen, collagen/bioglass, and collagen/bioglass/polycaprolactone.
Results showed that hDPCs grew significantly better on the collagen/bioglass and collagen/bioglass/polycaprolactone scaffolds compared to the collagen scaffold, particularly after two and three weeks, indicating enhanced cell proliferation and differentiation on the bioactive materials.