Villoglandular papillary adenocarcinoma of the uterine cervix: A report of 4 cases and a review of the literature.

To investigate the clinicopathological features, management and prognosis of villoglandular papillary adenocarcinoma (VGPA) of the uterine cervix, the current study presents 4 cases of VGPA of the uterine cervix. The median age of the patients was 55 years (range, 47-70 years), with all 4 patients presenting with stage Ib disease. Human papillomavirus (HPV) infection was detected in 3 patients; this was mainly HPV-16.

[Effects on the secretion of reproductive hormones in adult female rats exposed to lipopolysaccharide in neonatal life].

Objective: To explore whether neonatal endotoxin challenge alters reproductive hormone secretion in adult female rats.

Methods: Rats were intraperitoneally injected with lipopolysaccharide (LPS) or normal saline at postnatal days 3 and 5. At Week 12, the animals underwent bilateral oophorectomy and were exposed to LPS or saline.