Palladium(ii) complexes supported by PBP and POCOP pincer ligands: a comparison of their structure, properties and catalytic activity.

A Pd(ii) chloride complex supported by a Yamashita-Nozaki PBP pincer ligand, [C6H4-1,2-(NCH2PtBu2)2B]PdCl (1a), was synthesized. The structure, properties and catalytic activity of complex 1a were compared with those of the corresponding POCOP pincer complex [C6H3-2,6-(OPtBu2)2]PdCl (2a). It was found that the Pd centre in complex 1a is more electron rich and easier to be oxidized than that in complex 2a; complex 1a is a much better catalyst for Suzuki-Miyaura cross-coupling reactions than complex 2a.

Combination of the CYP2C19 metabolizer and the GRACE risk score better predicts the long-term major adverse cardiac events in acute coronary syndrome undergoing percutaneous coronary intervention.

Introduction: Both Global Registry of Acute Coronary Events (GRACE) risk score and CYP2C19 metabolizer status can independently predict major adverse cardiac events (MACEs) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). We investigated whether their combination could better predict MACE occurrence in patients with ACS undergoing PCI.

Materials And Methods: This retrospective cohort study included 548 consecutive patients with ACS undergoing PCI.

The Reactivity of Mercapto Groups against Boron Hydrides in Pincer Ligated Nickel Mercapto Complexes.

Several pincer ligated nickel mercapto complexes, [2,6-(R PCH ) C H ]NiSH (R=tBu, 1 a; iPr, 1 b), [2,6-(R PO) C H ]NiSH (R=tBu, 2 a; iPr, 2 b) and [4-MeOCO-2,6-(tBu PO) C H ]NiSH (3 a), were synthesized and fully characterized. The reactivity of the mercapto groups against boron hydrides and organic bases was investigated. It was found that the mercapto groups are difficult to be deprotonated by boron hydrides or organic bases.

Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis.

Hyponatremia is relevant to heart failure, liver cirrhosis and stroke, but the prognostic value of serum sodium levels in patients with acute coronary syndrome are still unclear. So we did a systematic review and meta-analysis to assess the prognostic value of hyponatremia on adverse events in patients after ACS. We systematically searched PubMed, Embase and Cochrane Library to find literatures which studied the prognostic value of hyponatremia in patients with ACS.

A reaction of [2,6-(BuPO)CH]NiSCHPh with BH·THF: borane mediated C-S bond cleavage.

C-S bond activation of thiophenols and mercaptans is of great importance but has rarely been reported. In this paper we report the C-S bond cleavage of the thiolato ligand of [2,6-(tBu2PO)2C6H3]NiSCH2Ph (1) mediated by BH3·THF. The treatment of 1 with an excess amount of BH3·THF in THF at room temperature afforded the borohydride complex [2,6-(tBu2PO)2C6H3]Ni(η2-BH4) (2) as the only product.

Hydroboration of CO catalyzed by bis(phosphinite) pincer ligated nickel thiolate complexes.

We report the hydroboration of CO with catecholborane catalyzed by a series of bis(phosphinite) pincer ligated nickel thiolate complexes. Turnover frequencies (TOFs) up to 2400 h were achieved at room temperature under an atmospheric pressure of CO. This represents the highest TOF value known to date for the reduction of CO to the methoxide level under mild conditions.

Highly efficient reduction of carbon dioxide with a borane catalyzed by bis(phosphinite) pincer ligated palladium thiolate complexes.

Highly efficient catalytic reduction of CO with catecholborane has been developed by using bis(phosphinite) pincer ligated palladium thiolate complexes. Turnover frequencies up to 1780 h have been achieved at room temperature under an atmospheric pressure of CO. These thiolate complexes represent the most efficient homogeneous catalysts known to date for the reduction of CO to methanol under mild conditions.