Hematopoiesis plays an important role(s) in maintenance and physiology of life. Hematopoiesis in vertebrates mainly includes self-renewal of the hematopoietic stem cells, proliferation and differentiation of the hematopoietic progenitor cells, and maturation of the blood cells. The regulation of hematogenesis involves a variety of transcription factors, membrane receptors, hematopoietic growth factors, and microRNAs, which interact with each other and form a variety of signaling pathways and signal networks.
View Article and Find Full Text PDFThe vertebrate vascular system development is a very important and complicated process. MicroRNAs regulate gene expression at transcriptional and post-transcriptional levels and play important roles in many physiological and pathological processes. MicroRNAs mainly participate in the regulation of vascular smooth muscle cell and vascular endothelial cell development.
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