Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County.

Background: The purpose of this study was to evaluate the association of multi-genotype polymorphisms with the stepwise progression of esophageal squamous cell cancer (ESCC) and the possibility of predicting those at higher risk.

Methods: A total of 1,004 subjects were recruited from Feicheng County, China, between Jan. 2004 and Dec.