Publications by authors named "Qiang Hou"

Background: Mitochondrial DNA copy number (mtDNAcn) is an effective biomarker to evaluate the effects of cationic metals on mtDNA integrity and function. In this study, we explored the relationships between individual and combined urinary metal concentrations and mtDNAcn among workers.

Methods: Blood mtDNAcn and urinary metal concentrations were quantified in a cohort of 328 participants.

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Since the discovery of high-temperature superconductivity in cuprates, understanding the unconventional pairing mechanism has remained one of the most significant challenges. The upper critical field (Hc2) is an essential parameter for obtaining information on the pair-breaking mechanism, coherence length, and pairing symmetry, all of which are crucial for understanding unconventional superconducting mechanisms. Here, we provide a brief review of studies onHc2in several representative series of cuprate, iron-based, and nickelate superconductors.

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Epithelial-to-mesenchymal transition (EMT) is a critical and complex process involved in normal embryonic development, tissue regeneration, and tumor progression. It also contributes to retinal diseases, such as age-related macular degeneration (AMD) and proliferative vitreoretinopathy (PVR). Although absent in melanoma 2 (AIM2) has been linked to inflammatory disorders, autoimmune diseases, and cancers, its role in the EMT of the retinal pigment epithelium (RPE-EMT) and retinal diseases remains unclear.

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Introduction: Cistanche deserticola Ma (CD), an edible and medicinal plant native to Xinjiang, Inner Mongolia, and Gansu in China, is rich in bioactive polysaccharides known for their health-promoting properties. The polysaccharides of C. deserticola (CDPs) have been shown to possess a range of beneficial activities, including immunomodulatory, anti-aging, antioxidant, and anti-osteoporosis effects.

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Article Synopsis
  • The study aimed to assess a new CT radiomics nomogram's ability to predict lymphovascular invasion (LVI) and perineural invasion (PNI) in patients with advanced gastric cancer.
  • Data from 149 patients were analyzed, revealing eight key radiomics features and other risk factors that significantly improved prediction accuracy for LVI/PNI.
  • The nomogram performed exceptionally well, achieving high accuracy rates in both training and validation groups, suggesting it could be a valuable tool for preoperative assessments in gastric cancer patients.
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Recent investigations of FeSe-based superconductors have revealed the presence of two superconducting domes and suggest possible distinct pairing mechanisms. Two superconducting domes are commonly found in unconventional superconductors and exhibit unique normal states and electronic structures. In this study, we conducted electromagnetic transport measurements to establish a complete phase diagram, successfully observing the two superconducting domes in FeSeS (0 ≤ ≤ 0.

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Objective: This study investigated the effect of forkhead box M1 (FOXM1) and Aurora kinase B (AURKB) on the epidermal function of keratinocytes.

Methods: Bioinformatics analysis was used to analyze the co-expression network of FOXM1 and its correlation with AURKB. The expression of FOXM1 and AURKB in tissues and cells was detected by immunofluorescence and real-time quantitative polymerase chain reaction, respectively.

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Triptophenolide, a major diterpenoid extracted from Hook. f., has been reported to possess significant anti-tumour, anti-androgen and anti-inflammatory activities.

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Cistanche deserticola Y. C. Ma (CD), is mainly distributed in the regions of China (Xinjiang, Inner Mongolia, Gansu), Mongolia, Iran and India.

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Six novel bacterial strains, designated N016, N017, N022, N028, N056, and N064, were isolated from soil sampled on the Qinghai-Tibet Plateau. Cells were aerobic, orange or yellow, globular or rod-shaped, non-motile, non-spore-forming, Gram-stain-positive, catalase-positive and oxidase-negative. All the isolates were salt-tolerant and could grow in the range of 4-42 °C.

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Gastric cancer is a prevalent malignant tumor worldwide, posing challenges due to its poor prognosis and limited treatment options. Cancer stem cells (CSCs) were demonstrated as a subset of cancer cells responsible for tumor initiation and progression, and their inherent resistance to conventional chemotherapy and radiotherapy critically contributes to tumor recurrence and metastasis. Promoting the eradication of cancer stem cells is crucial for enhancing the efficacy of cancer treatments.

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Article Synopsis
  • - Nonalcoholic fatty liver disease (NAFLD), particularly nonalcoholic steatohepatitis (NASH), is a common chronic liver condition, and the Yanxiao Di'naer formula (YXDNE) from Uyghur traditional medicine has been used historically to treat liver issues, though its effectiveness and mechanisms in NASH remain poorly defined.
  • - This study aimed to evaluate the effectiveness of YXDNE for treating NASH using a high-fat, high-cholesterol diet and carbon tetrachloride in mice, alongside detailed analysis of its components and mechanisms involving various metabolic pathways.
  • - Results indicated that YXDNE significantly improved NASH in mice by influencing fatty acid metabolism and activating key signaling
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Gastric cancer stem cells (GCSCs) originate from both gastric adult stem cells and bone marrow cells and are conspicuously present within the histological milieu of gastric cancer tissue. GCSCs play pivotal and multifaceted roles in the initiation, progression, and recurrence of gastric cancer. Hence, the characterization of GCSCs not only facilitates precise target identification for prospective therapeutic interventions in gastric cancer but also has significant implications for targeted therapy and the prognosis of gastric cancer.

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Ischemic stroke (IS) can cause severe harm, inducing oxidative stress, inflammation, and pyroptotic death. IS treatment efficacy remains limited, and microglia are important regulators of IS-related blood-brain barrier (BBB) damage. It is thus vital that new therapeutic agents capable of targeting microglia be identified to treat IS-related damage to the BBB.

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Background: The transaxillary approach of breast augmentation is the most popular method in Asia, but longer period of recovery was observed in spite of the assistance of endoscope.

Objectives: Introducing the ultrasonic dissection devices might be a solution to minimizing tisue damage thus relieving pain and shortening the period of recovery.

Method: Between March 2020 and September 2022, we retrospectively reviewed the cases of 122 patients underwent endoscopic augmentation mammoplasty via the transaxillary approach using either the monopolar electrotome (ME) alone or assisted with Harmonic Scalpel (HS) in defining the retropectoral pocket and severing the pectoralis major muscle.

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A novel alkaliphilic, Gram-stain-positive, moderately halophilic, rod-shaped, endospore-forming, motile, facultatively anaerobic bacterium (DQ-9) was isolated from a sediment sample collected from Daqing oilfield in China, and characterized by a polyphasic taxonomic approach. Strain DQ-9 formed yellow pigment and grew occurred at salinities of 1-12 % (w/v) NaCl (optimum, 8 %) and at 10-40 °C (optimum, 30-35 °C), at pH 7.5-10.

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Background: Perioperative nursing can reduce the stress reaction and improve the prognosis of children.

Aim: To elucidate the influence of multidisciplinary collaborative nursing for enhanced recovery after surgery (ERAS) with family care in perioperative nursing children with an inguinal hernia and its impact on the prognosis.

Methods: The data of 100 children with inguinal hernia were retrospectively analyzed.

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Accumulating evidence indicates that mA methyltransferase 3 (METTL3) plays a pivotal role in different malignancies including melanoma. However, the function and underlying mechanisms by which METTL3 contributes to the tumorigenesis of melanoma remain undocumented. The association of METTL3 and long noncoding RNA (lncRNA) small nucleolar RNA host gene 3 (SNHG3) with clinicopathological characteristics and prognosis in patients with melanoma was analyzed by real-time quantitative polymerase chain reaction (RT-qPCR), Western blotting, and The Cancer Genome Atlas data sets.

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The 11 system in the iron-based superconducting family has become one of the most extensively studied materials in the research of high-temperature superconductivity, due to their simple structure and rich physical properties. Many exotic properties, such as multiband electronic structure, electronic nematicity, topology and antiferromagnetic order, provide strong support for the theory of high-temperature superconductivity, and have been at the forefront of condensed matter physics in the past decade. One noteworthy aspect is that a high upper critical magnetic field, large critical current density and lower toxicity give the 11 system good application prospects.

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The service-oriented digital transformation of the construction industry is a development trend of cross-border industrial integration and transformation and upgrading in the digital economy environment, and collaborative value creation among stakeholders is seen as a strategic imperative to promote this process. This study aims to achieve efficient collaborative value co-creation and accelerate the digital transformation process of the construction industry by exploring the collaborative strategies and evolution laws of value co-creators in the digital service ecosystem of the construction industry. Based on evolutionary game theory and methods, this paper analyzes the evolutionary stability strategies and conditions of each participant in the service-oriented value chain at different stages of the digital transformation of the construction industry.

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Gene mutation is a basic evolutionary mechanism in plants under selection pressure of herbicides. Such mutation has pleiotropic effects on plant growth. We systemically investigated the effects of Pro106Leu (P106L), Pro106Ser (P106S), and Thr102Ile + Pro106Ser (TIPS) mutations on EPSPS functionality and fitness traits in at the biochemical and physiological levels.

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Article Synopsis
  • Nicotine dependence is a major public health issue, and this study focused on how family functioning affects nicotine dependence in smoking fathers, leveraging the McMaster model of family functioning for insights.
  • The study involved 874 fathers from Qingdao, with assessments of nicotine dependence using the Fagerstrom test and family functioning through the Family Assessment Device. Results showed varying levels of dependence among participants.
  • Findings indicated that poorer family functioning, lower education, more alcohol use, and longer smoking duration were linked to severe nicotine dependence, while starting smoking at an older age and higher education levels were associated with less severe dependence.
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Cognitive impairment is the main central nervous system complication of diabetes, affecting the quality of life of patients. is a homologous plant widely used as a health food and therapeutic drug. Verbascoside, a signature component of , has anti-diabetic and neuroprotective effects.

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Epithelial-mesenchymal transition (EMT) of the retinal pigment epithelium (RPE) is a hallmark of the pathogenesis of proliferative vitreoretinopathy (PVR) that can lead to severe vision loss. Nevertheless, the precise regulatory mechanisms underlying the pathogenesis of PVR remain largely unknown. Here, we show that the expression of death-associated protein-like 1 (DAPL1) is downregulated in PVR membranes and that DAPL1 deficiency promotes EMT in RPE cells in mice.

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Testing-culling is a very effective measure for the prevention and control of animal diseases. In this paper, based on sheep brucellosis control policies and animal testing characteristics and considering the limitation of culling resources, a dynamic model is established to study the impact of testing-culling measure. Theoretical analysis reveals that the model may have one or three positive equilibria.

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