Synopsis of recent research by authors named "Qian-fan Yang"
- Qian-Fan Yang's recent research centers on the discovery and study of G-quadruplex (G4) and i-Motif ligands, leading to the development and updates of the G4 Ligand Database (G4LDB), which provides insights into non-canonical nucleic acid structures that have significant biological implications.
- The findings emphasize the structural diversity of G4/iM ligands and their potential applications in therapeutic contexts, fostering interest in how small molecules can selectively target these unique nucleic acid formations for various chemical and biological applications.
- Additionally, Yang has explored the interactions of various compounds, including cyanine dyes and flavonoids, with proteins like human serum transferrin, advancing the understanding of molecular recognition and potential drug delivery mechanisms in the context of cancer treatment.
