Publications by authors named "Qian-Yun Pang"

Article Synopsis
  • The study investigates how intraoperative temperatures, both hypothermia (below 36°C) and hyperthermia (above 37.3°C), affect the risk of postoperative pulmonary infections (PPI) and surgical site infections (SSI) in patients undergoing major non-cardiac surgeries under general anesthesia.
  • Findings revealed that longer durations of hypothermia (>90 min) and hyperthermia (>75 min) significantly increased the likelihood of PPI, while prolonged hypothermia (>195 min) and hyperthermia also raised the risk of SSI.
  • Overall, the research concluded that variations in body temperature during surgery are linked to higher rates of postoperative infections, emphasizing the need for careful temperature
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Study Objective: During cesarean section, hypotension is a frequent side effect of spinal anesthesia. As a sitting or lateral position is required for spinal anesthesia performance, which of these two positions is more likely to cause intraoperative nausea, vomiting, and hypotension is still unknown. This meta-analysis compared the effects of these two positions on maternal hemodynamics and intraoperative nausea and vomiting.

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Background: Noradrenaline (NA) is commonly used intraoperatively to prevent fluid overload and maintain hemodynamic stability. Clinical studies provided inconsistent results concerning the effect of NA on postoperative outcomes. As aging is accompanied with various diseases and has the high possibility of the risk for postoperative complications, we hypothesized that intraoperative NA infusion in older adult patients undergoing major non-cardiac surgeries might potentially exert adverse outcomes.

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Background: Regional anesthesia have been successfully performed for pain management in breast cancer surgery, but it is unclear which is the best regional anesthesia technique. The aim of the present network meta-analysis was to assess the analgesic efficacy and disadvantages of regional anesthesia techniques.

Methods: Multiple databases were searched for randomized controlled trials (RCTs).

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Background: Dexamethasone is commonly used for antiemesis in surgical patients. It has been confirmed that long-term steroid use increases blood glucose level in both diabetic and non-diabetic patients, it is unclear how a single dose of intravenous dexamethasone used pre/intraoperatively for postoperative nausea and vomiting (PONV) prophylaxis would influence the blood glucose and wound healing in diabetic patients.

Methods: The Pubmed, Cochrane Library, Embase, Web of Science databases, CNKI and Google Scholar were searched.

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Objectives: To develop and validate a nomogram for predicting postoperative pulmonary infection (PPI) in patients undergoing lung surgery.

Design: Single-center retrospective cohort analysis.

Setting: A university-affiliated cancer hospital PARTICIPANTS: A total of 1,501 adult patients who underwent lung surgery from January 2018 to December 2020.

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Background: Postoperative cognitive dysfunction (POCD) is a very common event in elderly noncardiac surgical patients. The effects of inhalational anaesthetics and propofol on the incidence of POCD and postoperative cognitive status at different time points after surgery are currently unclear.

Methods: We searched the Embase, Medline, Cochrane Library, and Web of Science databases for randomized controlled trials (RCTs), in which inhalation anaesthesia and propofol anaesthesia were compared.

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Article Synopsis
  • General anaesthesia is typically used during breast cancer surgery, but the study compares inhalational anaesthesia and propofol-based intravenous anaesthesia to determine which is better for patient outcomes.
  • A meta-analysis of 20 randomized controlled trials with 2201 patients showed that propofol-based anaesthesia leads to less postoperative nausea and vomiting but requires more rescue analgesia than inhalational anaesthesia.
  • Propofol-based anaesthesia also helps preserve immune function and improves the two-year recurrence-free survival rate, though it doesn’t significantly influence overall recurrence or survival rates.
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Background: Intra-operative hypotension might induce poor postoperative outcomes in non-cardiac surgery, and the relationship between the level or duration of Intra-operative hypotension (IOH) and postoperative adverse events is still unclear. In this study, we performed a meta-analysis to determine how IOH could affect acute kidney injury (AKI), myocardial injury and mortality in non-cardiac surgery.

Methods: We searched PubMed (Medline), Embase, Springer, The Cochrane Library, Ovid and Google Scholar, and retrieved the related clinical trials on intra-operative hypotension and prognosis in non-cardiac surgery.

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Background: Perioperative transfusion can reduce the survival rate in colorectal cancer patients. The effects of transfusion on the short- and long-term prognoses are becoming intriguing.

Objective: This systematic review and meta-analysis aimed to define the effects of perioperative transfusion on the short- and long-term prognoses of colorectal cancer surgery.

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Introduction: There is a high incidence of postoperative cardiopulmonary complications after thoracic surgery with one lung ventilation (OLV), the effect of general anesthetics on intraoperative cardiopulmonary function and postoperative complications is still unclear.

Evidence Acquisition: We searched the Embase, PubMed, Cochrane Library, Springer, Wiley, CNKI, VIP and Wanfang databases for randomized controlled trials (RCTs) in which inhalation anesthesia and intravenous anesthesia were compared; intraoperative cardiopulmonary function and postoperative complications were assessed in patients undergoing thoracic surgery with intraoperative one-lung ventilation (OLV).

Evidence Synthesis: Twenty-three RCTs with a total of 1349 patients were included.

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Introduction: Postoperative major adverse cardiac events (MACEs) are the main cause of postoperative mortality, and controversies exist regarding the effects of anesthesia methods on postoperative MACEs and mortality in high-risk cardiac patients after non-cardiac surgeries.

Evidence Acquisition: A Meta-analysis about the effect of anesthesia methods on postoperative MACEs and mortality in high-risk cardiac patients undergoing intermediate- or high-risk non-cardiac surgeries was conducted; Chinese databases (SinoMed, CNKI, Wanfang, and VIP) and English databases (Medline, EMBASE, PubMed, Springer, Ovid, the Cochrane Library, and Google scholar) were searched.

Evidence Synthesis: Twenty-seven randomized controlled trials (RCTs) were included and 35340 patients were involved.

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