Publications by authors named "Qian-Yao Cheng"
: Systemic lupus erythematosus (SLE) is an autoimmune disease with complex etiology. Intercellular cell adhesion molecule-1 (ICAM-1) is critical for leukocyte adhesion to endothelium and migration out of blood vessels and thus participates in many autoimmune diseases. Previous studies of blood and urinary ICAM-1 in SLE have yielded inconsistent results.
View Article and Find Full Text PDF: To identify accurate occurrence and risk of cardiovascular (CV) events (stroke and myocardial infarction [MI]) in patients with systemic lupus erythematosus (SLE). : Systemic literature search in PubMed and additional manual search were performed to obtain interested studies until March 31, 2018. The pooled incidences and risk of stroke and MI were calculated.
View Article and Find Full Text PDFBackground And Objectives: Insulin-like growth factor-1 (IGF-1) levels have been investigated in rheumatoid arthritis (RA), however, produced inconsistent results. The purpose of this meta-analysis was to derive a more precise conclusion about serum/plasma IGF-1 levels in RA patients.
Methods: PubMed, Embase and the Cochrane Library databases were searched up to December 2018 in English, and the studies comparing serum/plasma IGF-1 levels between RA group and healthy control group were what we are interested in.
Article Synopsis
- The study investigated the diagnostic value of anti-keratin antibodies (AKA) in patients with rheumatoid arthritis (RA), showing its high specificity as a potential diagnostic tool.
- A total of 15 studies were analyzed, revealing a pooled sensitivity of 46% and a pooled specificity of 94% for AKA in diagnosing RA, alongside a diagnostic odds ratio of 15.86.
- The findings suggest that while AKA has significant specificity, its sensitivity indicates that it may not be the sole diagnostic method for RA; further evaluation in clinical practice is recommended.