[The Antileukemia Activity of ZSTK474 on U937 Cells].

Objective: To investigate the antileukemia activity of phosphatidylinositol-3 kinase (PI3K) inhibitor ZSTK474 on human leukemia cell line U937.

Methods: MTT, soft agar assay, flow cytometric analysis and western blot were used to detect the effect of ZSTK474 on U937 cell proliferation, tumorigenicity, cell cycle, cell apoptosis and phosphorylation levels of the key factor of PI3K/AKT pathway. Chou-Talalay method was used to evaluate the combination of ZSTK474 with Cytarabine or Homoharringtonine.

[Effects of digital information display time on human and machines monitoring performance].

Objective: To provide an index for function allocation of information monitoring between human and machine by studying the effect of digital information display time on human or machine monitoring performance.

Method: Two computers were used. One computer, ten numbers with two decided digits were displayed randomly for three times.

[Experimental study on human reaction of determination and performance in virtual environment].

Objective: To study factuality of ergonomic experimental data from subjects performing virtual environment wearing head mounted display (HMD) and data gloves, so as to improve the reliability of the application of virtual reality in manned spaceflight (e.g. human-machine interface design scheme ergonomic evaluation, and virtual training).

[Human-centered ergonomical study and applications in manned spacecraft project of China].

High G and weightlessness are two important environment factors that are unavoidable during spaceflight. They will bring key effects on astronauts' posture and working efficiency. In this paper, on the basis of experience of China first manned spacecraft project in the past 10 years, the concept of space ergonomics and its role in the project were reviewed.

[Effects of field viewing angles on object judgement [correction of jubgerent] in virtual environment].

Object: To investigate the effect of viewing angle on human judgement reliability for objects in virtual environment.

Method: Firstly, pre-tests were done with the PC virtual reality ergonomic system to determine difference among observed object and values of viewing angle. Then, one factor, 4-levels full random experiments were done with 45 health human subjects (male and female nearly 1:1).